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Displaying results 8721 - 8730 of 10000 in total
  1. Drug

    CHIR-124

    go.drugbank.com/drugs/DB06852
    Experimental

    CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

  2. Drug

    Tretazicar

    go.drugbank.com/drugs/DB04253
    Investigational

    Tretazicar is under investigation in clinical trial NCT00746590 (Study of Anti-tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma).

  3. Drug

    S-23

    go.drugbank.com/drugs/DB07419
    Experimental

    An androgen receptor modulator.

    Synonyms: (2S)-3-(4-Chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide
  4. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. … These exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis and tissue repair.

  5. Drug

    Aldafermin

    go.drugbank.com/drugs/DB16086
    Investigational

    Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center … Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).

    Synonyms: (phe5>met,ser6>arg,ala8>ser,gly9>ser,his11>leu) fibroblast growth factor 19 (human fgf19) (5-194)-peptide, produced in escherichia coli
  6. Drug

    Famprofazone

    go.drugbank.com/drugs/DB16702
    Experimental

    Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. … [A236369,L34724] Famprofazone is included in the list of prohibited substances specified by the ‘World Anti-Doping Agency’ (WADA).[L34729]

  7. Drug

    RO7830698

    go.drugbank.com/drugs/DB33974
    Experimental

    RO7830698 is a biologic drug. RO7830698 is under investigation in clinical trial NCT07822334 (A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease).

  8. Drug

    MEDI6012

    go.drugbank.com/drugs/DB14833
    Investigational

    Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction

  9. Drug

    BMS-986141

    go.drugbank.com/drugs/DB14942
    Investigational

    BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).

  10. Drug

    IO-202

    go.drugbank.com/drugs/DB17548
    Investigational

    IO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.