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CH-1504 L-isomer
go.drugbank.com/drugs/DB19052InvestigationalCH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Synonyms: 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid, L-glutamic acid, n-(4-(2-(2,4-diamino-6-quinazolinyl)ethyl)benzoyl)-4-methylene-Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-Gluconolactone
go.drugbank.com/drugs/DB04564ApprovedGluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. … Pure gluconolactone is a white odorless crystalline powder.
Synonyms: 1,5-D-gluconolactone, D-glucono-1,5-lactoneRineterkib
go.drugbank.com/drugs/DB17560InvestigationalRineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel … Ruxolitinib Combinations in Myelofibrosis Patients).
Synonyms: 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl)-2-fluorobenzamide, Benzamide, 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl)-2-fluoro-Foscarbidopa
go.drugbank.com/drugs/DB16171ApprovedFoscarbidopa is under investigation in clinical trial NCT04379050 (Extension Study to Evaluate Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Adult
Quinupramine
go.drugbank.com/drugs/DB13246ApprovedQuinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003].
Gemcabene
go.drugbank.com/drugs/DB05123InvestigationalGemcabene is a new drug that lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C).
Iodocetylic acid I-123
go.drugbank.com/drugs/DB19593ExperimentalIodocetylic acid I-123 is a small molecule drug. Iodocetylic acid I-123 has a monoisotopic molecular weight of 378.14 Da.
Synonyms: Iodocetylic acid i 123, Iodocetylic acid (123 i)Tirabrutinib
go.drugbank.com/drugs/DB15227InvestigationalTirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
AVR-RD-02
go.drugbank.com/drugs/DB17650InvestigationalAVR-RD-02 is being investigated in Gaucher Disease.[L45958] … It consists of autologous CD34+ enriched hematopoietic stem cells (HSCs) that have been genetically modified _ex vivo_ with a lentiviral vector (LV) to contain a ribonucleic acid (RNA) transcript that,