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Aprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
Mixtures: EMEND® 80 MG/125 MG, EMEND® 80 MG/125 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersAbciximab
go.drugbank.com/drugs/DB00054ApprovedWithdrawnAbciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3.
Products: CLOTİNAB 10 MG/5 ML IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 1 ADET, ReoPro 2 mg/ml Injektionslösung oder InfusionslösungFulvestrant
go.drugbank.com/drugs/DB00947ApprovedInvestigationalIt is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. … Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy.
Synonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPrucalopride
go.drugbank.com/drugs/DB06480ApprovedInvestigational[A37348] The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. … Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RESOLOR ® TABLETAS RECUBIERTAS DE 2 MG, RESOLOR ® TABLETAS RECUBIERTAS DE 1 MGPentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Products: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. … When labelled with technetium Tc99m, dextran 75 is intravenously administered as an imaging agent to detect and diagnose conditions in the vascular compartment such as pericardial effusion or ventricular
Salts: Dextran sulfate sodium (MW 5000), Dextran sulfate sodium (MW 9500)Mixtures: POLİFLEKS 100 MG/ML DEKSTRAN 40+9 MG/ML İZOTONİK SODYUM KLORÜR I.V. İNFÜZYON İÇİN ÇÖZELTİ, 150 ML SETLİ(PVC), POLİFLEKS 100 MG/ML DEKSTRAN 40+9 MG/ML İZOTONİK SODYUM KLORÜR I.V. İNFÜZYON İÇİN ÇÖZELTİ, 150 ML SETSİZ(PVC)Bacitracin
go.drugbank.com/drugs/DB00626ApprovedInvestigationalVet approvedBacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.
Synonyms: Bacitracin AMixtures: THIOCILLINE 500 IU/G + 5 MG/G DERİ MERHEMİ, 30 G, THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GRPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalDue to the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and Johnson Company. … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B.
Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (10 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet)Estradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approved[DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation
Mixtures: AI PROFAMILIA, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Nu-zopiclone, Nu-zopiclone Tablets - 7.5mg