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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Vonoprazan

    go.drugbank.com/drugs/DB11739
    ApprovedInvestigational

    [A253707] In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and as an adjunct to _Helicobacter pylori_ (_H. pylori_) eradication. … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations.

    Categories: Alimentary Tract and Metabolism, vonoprazan and amoxicillinSynonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
  2. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).

    Mixtures: Fosinopril Sodium and Hydrochlorothiazide, Fosinopril Sodium and HydrochlorothiazideCategories: ACE Inhibitors and Diuretics, fosinopril and diuretics
  3. Drug

    Ambrosia confertiflora pollen

    go.drugbank.com/drugs/DB10872
    Approved

    Ambrosia confertiflora pollen is the pollen of the Ambrosia confertiflora plant. Ambrosia confertiflora pollen is mainly used in allergenic testing.

    Synonyms: weakleaf bur ragweed pollen extract
  4. Drug

    Ebastine

    go.drugbank.com/drugs/DB11742
    ApprovedInvestigationalWithdrawn

    Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.

    Products: EBASTEL 10MG, EBASTIN ARISTO 10MG
  5. Drug

    Saxagliptin

    go.drugbank.com/drugs/DB06335
    ApprovedInvestigational

    Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.

    Mixtures: KOMBIGLYZE XR TABLET 5MG/500MG, KOMBIGLYZE XR TABLET 5MG/1000MGCategories: Drugs Used in Diabetes, DPP-IV Inhibitors
  6. Drug

    Romosozumab

    go.drugbank.com/drugs/DB11866
    ApprovedInvestigational

    Romosozumab prevents bone resorption and induces the formation of bone though it is associated with an increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. … Romosozumab also demonstrates a faster and larger increase in bone density than teriparatide[A177050]. Romosozumab is marketed in the United States by Amgen under the brand name Evinity[L5921].

    Categories: Amino Acids, Peptides, and Proteins, Drugs Affecting Bone Structure and MineralizationProducts: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML
  7. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    In murine tumors and human tumor xenografts, vinflunine exhibits an antitumor efficacy than [DB00361], [DB00570], and [DB00541] [A31975]. … In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626].

    Categories: Antineoplastic and Immunomodulating AgentsProducts: JAVLOR 250MG/10ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, JAVLOR 50MG/2ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET
  8. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Mixtures: PIPERACILINA/TAZOBACTAM 4G/500MG, Tazocin Pws IV 2g Piperacillin-.25g Tazobac.Products: Pipracil-pws IV Im 2g/vial, Pipracil-pws IV Im 3g/vial
  9. Drug

    Lormetazepam

    go.drugbank.com/drugs/DB13872
    Approved

    Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.

    Categories: Hypnotics and Sedatives, Benzodiazepines and benzodiazepine derivativesSynonyms: N-Methyllorazepam
  10. Drug

    Nilotinib

    go.drugbank.com/drugs/DB04868
    ApprovedInvestigational

    A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec … Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML).

    Categories: Antineoplastic and Immunomodulating AgentsProducts: TASIGNA CAPSULE 50MG, Tasigna 50mg Capsules