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T487
go.drugbank.com/drugs/DB05474ExperimentalThe formulation is administered orally and has anti-inflammatory effects in conditions such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.
VX-702
go.drugbank.com/drugs/DB05470InvestigationalIn the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Tirapazamine
go.drugbank.com/drugs/DB04858InvestigationalTirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions. … This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia.
SF1126
go.drugbank.com/drugs/DB05210InvestigationalSF1126 is an integrin-targeted PI3 kinase inhibitor.
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt was determined that polaprezinc may be effective in pressure ulcer treatment [A31856]. … It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308].
International brands: Promac-DCitatuzumab Bogatox
go.drugbank.com/drugs/DB06072InvestigationalVB6-845 has demonstrated effective cancer cell killing properties in pre-clinical tests.
Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
go.drugbank.com/drugs/DB10076ApprovedHaemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by *Haemophilus … vaccine contains the *Haemophilus influenzae* type b capsular polysaccharide (polyribosyl-ribitol-phosphate, PRP), a high-molecular-weight polymer prepared from the *H. influenzae* type b strain 1482 grown in
RDP58
go.drugbank.com/drugs/DB06566ExperimentalRDP58 (NH2-arg-norleucine (nle)-nle-arg-nle-nle-nle-gly-tyr-CONH2) (Sangstat Corp., Fremont, California) is a novel synthetic peptide that inhibits early signal transduction pathways for the expression of inflammatory cytokines.
PA-1050040
go.drugbank.com/drugs/DB06039ExperimentalPA1050040, a second generation HIV-1 maturation inhibitor, is a chemical analog of Bevirimat (BVM). It inhibits virus replication by the same mechanism of action as BVM.
Camptothecin
go.drugbank.com/drugs/DB04690InvestigationalCamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.
Synonyms: D-camptothecin