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Displaying results 8811 - 8820 of 10000 in total
  1. Drug

    Vidutolimod

    go.drugbank.com/drugs/DB17500
    Investigational

    Vidutolimod is a Toll-like receptor 9 (TLR9) agonist. It is an investigational cancer vaccine.

    Synonyms: Dna, d(g-g-g-g-g-g-g-g-g-g-g-a-c-g-a-t-c-g-t-c-g-g-g-g-g-g-g-g-g-g), Cmp-001 component cpg-a oligodeoxynucleotide tlr9 agonist
  2. Drug

    Vibecotamab

    go.drugbank.com/drugs/DB18872
    Investigational

    Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).

    Synonyms: Anti-cd123 x anti-cd3 bispecific antibody xmab14045
  3. Drug

    1-Testosterone

    go.drugbank.com/drugs/DB01481
    IllicitInvestigational

    1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.

    Synonyms: 17beta-hydroxy-5alpha-androst-1-en-3-one, 1-T
  4. Drug

    Tylosin

    go.drugbank.com/drugs/DB11475
    ExperimentalVet approved

    Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. … It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.

    Mixtures: Tylan 40 Sulfa-G PremixSynonyms: Tylosin A
  5. Drug

    Temanogrel

    go.drugbank.com/drugs/DB05227
    Investigational

    APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena. … APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists
  6. Drug

    Zastumotide

    go.drugbank.com/drugs/DB14926
    Investigational

    It is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck). … Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R.

    Synonyms: Astuprotimut R, Astuprotimut-R
  7. Drug

    Dabocemagene autoficel

    go.drugbank.com/drugs/DB17878
    Investigational

    Dabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. … Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797]

    Synonyms: D-Fi, THE CONTROL OF A HUMAN CYTOMEGALOVIRUS (CMV) PROMO
  8. Drug

    DYNE-251

    go.drugbank.com/drugs/DB18130
    Investigational

    It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping. … DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1).

  9. Drug

    Pegapamodutide

    go.drugbank.com/drugs/DB14817
    Investigational

    Pegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).

  10. Drug

    Icrucumab

    go.drugbank.com/drugs/DB14824
    Investigational

    Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).