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Displaying results 8821 - 8830 of 9698 in total
  1. Drug

    Luveltamab tazevibulin

    go.drugbank.com/drugs/DB17563
    Investigational

    [A257414] It is under investigation in clinical trial NCT05200364 (A Study of STRO-002, an Anti-folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer

  2. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain
  3. Drug

    SS1(dsFv)-PE38

    go.drugbank.com/drugs/DB17579
    Investigational

    SS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin. … SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma

  4. Drug

    Mezigdomide

    go.drugbank.com/drugs/DB17584
    Investigational

    Mezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants

  5. Drug

    FB-825

    go.drugbank.com/drugs/DB17598
    Investigational

    FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells.

  6. Drug

    Rexlemestrocel-L

    go.drugbank.com/drugs/DB17606
    Investigational

    Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product.

    Synonyms: Rexlemestrocel-L
  7. Drug

    CDX-6210

    go.drugbank.com/drugs/DB17610
    Experimental

    CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_.

  8. Drug

    Ergothioneine

    go.drugbank.com/drugs/DB17614
    Investigational

    Synonyms: L-ergothioneine, L-(+)-ergothioneineCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Zodasiran

    go.drugbank.com/drugs/DB17626
    Investigational

    ARO-ANG3 is a subcutaneously administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 (ANGPTL3).

    Categories: Antisense Elements (Genetics)
  10. Drug

    RGX-111

    go.drugbank.com/drugs/DB17632
    Investigational

    RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene.

    Synonyms: Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase