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Bictegravir
go.drugbank.com/drugs/DB11799ApprovedInvestigationalBictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. … It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677]
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesErtugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigationalErtugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus.
Categories: P-glycoprotein substrates, Sodium-Glucose Transporter 2 InhibitorsSynonyms: (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol, 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranosePrulifloxacin
go.drugbank.com/drugs/DB11892InvestigationalPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
Categories: 4-Quinolones, Heterocyclic Compounds, 1-RingPridopidine
go.drugbank.com/drugs/DB11947InvestigationalPridopidine has been used in trials studying the treatment of Huntington's Disease.
Categories: Heterocyclic Compounds, 1-RingIlaprazole
go.drugbank.com/drugs/DB11964InvestigationalIlaprazole has been investigated in Helicobacter Infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADETCarbon black
go.drugbank.com/drugs/DB11980InvestigationalProduced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.
Synonyms: D&C black no. 2, D&C BLACK NO. 2 [II]Elamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigational[A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.
Categories: MATE 1 InhibitorsNirogacestat
go.drugbank.com/drugs/DB12005ApprovedInvestigationalNirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesOzagrel
go.drugbank.com/drugs/DB12017InvestigationalOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Categories: Thromboxane-A Synthase, antagonists & inhibitorsEvatanepag
go.drugbank.com/drugs/DB12022InvestigationalEvatanepag has been used in trials studying the treatment of Tibial Fractures.
Categories: Heterocyclic Compounds, 1-Ring