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Moxaverine
go.drugbank.com/drugs/DB12251InvestigationalMoxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
Categories: Heterocyclic Compounds, 2-RingPlatinum
go.drugbank.com/drugs/DB12257InvestigationalPlatinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and
Categories: Compounds used in a research, industrial, or household settingLosmapimod
go.drugbank.com/drugs/DB12270InvestigationalLosmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
Categories: Heterocyclic Compounds, 1-RingORE-1001
go.drugbank.com/drugs/DB12271InvestigationalIt is an ACE2 inhibitor.
Categories: Heterocyclic Compounds, 1-RingEcopipam
go.drugbank.com/drugs/DB12273InvestigationalEcopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.
Categories: Heterocyclic Compounds, 2-RingSeviteronel
go.drugbank.com/drugs/DB12275InvestigationalSeviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Enzyme InhibitorsLuspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigationalLuspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1. … [A187835] Luspatercept's novel mechanism of action, then, is uniquely suited for the treatment of conditions in which late-stage erythropoiesis is defective, such as beta thalassemia and other myelodysplastic
Products: REBLOZYL®Defactinib
go.drugbank.com/drugs/DB12282ApprovedInvestigationalDefactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … [L53198,L53208] FAK is important for the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, and its upregulation is a key
Synonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideCategories: MATE 2 Inhibitors, Cytochrome P-450 SubstratesBalapiravir
go.drugbank.com/drugs/DB12283InvestigationalBalapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.
LY-2608204
go.drugbank.com/drugs/DB12284InvestigationalLY2608204 has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-Ring