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LioCyx-M004
go.drugbank.com/drugs/DB17368InvestigationalLioCyx-M004 are autologous T cells transduced with a retroviral vector encoding a hepatitis B virus antigen-specific T cell receptor.
Synonyms: mRNA HBV/TCR T-cellsTBX-3400
go.drugbank.com/drugs/DB17370InvestigationalTBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.
P-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Synonyms: Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T cells)Zanolimumab
go.drugbank.com/drugs/DB17376InvestigationalZanolimumab is a fully human monoclonal antibody directed against CD4.
Bersanlimab
go.drugbank.com/drugs/DB17377InvestigationalBersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Synonyms: Anti-icam-1 monoclonal antibody bi-505, Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibodyMVR-T3011
go.drugbank.com/drugs/DB17378InvestigationalMVR-T3011 is a genetically modified oncolytic Herpes Simplex Virus (HSV-1) with 2 exogenous genes encoding the active heterodimer human interleukin 12 (IL-12) and the Fab fragment of an anti-human PD-1
Xenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalThey undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal. … [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile, but its use in other applications has affected its availability.
Synonyms: Xenon, isotope of mass 129m(8.88 d)Becotatug vedotin
go.drugbank.com/drugs/DB17407InvestigationalMRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.
KITE-585
go.drugbank.com/drugs/DB17409InvestigationalKITE-585 is an autologous, fully-human anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cell therapy. It is being investigated in the treatment of multiple myeloma.
TNG908
go.drugbank.com/drugs/DB17411InvestigationalTNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5).