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Displaying results 8871 - 8880 of 10000 in total
  1. Drug

    Sifalimumab

    go.drugbank.com/drugs/DB12773
    Investigational

    Sifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients. … The levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disease activity.

  2. Drug

    Ganulameran

    go.drugbank.com/drugs/DB16442
    Investigational

    As such, BNT162b3 has entered a phase I/II study in early September 2020 (NCT04537949). … Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it.

  3. Drug

    Relutrigine

    go.drugbank.com/drugs/DB21614
    Investigational

    The usage of the INN stem '-trigine' in the name indicates that Relutrigine is a sodium channel blocker, signal transduction modulator. … Relutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).

  4. Drug

    Lodenafil carbonate

    go.drugbank.com/drugs/DB11927
    Investigational

    Lodenafil carbonate has been used in trials studying the treatment of Coronaropathy and Erectile Dysfunction.

  5. Drug

    AZD-4818

    go.drugbank.com/drugs/DB12002
    Investigational

    AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD).

  6. Drug

    Polydioxanone

    go.drugbank.com/drugs/DB14832
    Investigational

    Polydioxanone is under investigation in clinical trial NCT00998907 (PDS*Plus and Wound Infections After Laparotomy).

  7. Drug

    Tarloxotinib

    go.drugbank.com/drugs/DB14944
    Investigational

    Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations).

  8. Drug

    4-isothioureidobutyronitrile

    go.drugbank.com/drugs/DB13010
    Investigational

    Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.

  9. Drug

    Fosdagrocorat

    go.drugbank.com/drugs/DB12198
    Investigational

    Fosdagrocorat has been used in trials studying the treatment and basic science of Rheumatoid Arthritis.

  10. Drug

    Begacestat

    go.drugbank.com/drugs/DB12263
    Investigational

    Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.