Begacestat

DB12263InvestigationalSmall molecule

Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.

Chemical structure of Begacestat
Formula / weight
C9H8ClF6NO3S2 · 391.73 g/mol (avg)
Code names
GSI-953

Resolves to

Compound
UNII3666C56BBUCAS769169-27-9ChEMBLCHEMBL463981PubChem11269353
Structure
InChIKeyPSXOKXJMVRSARX-SCSAIBSYSA-NSMILESOC[C@@H](NS(=O)(=O)C1=CC=C(Cl)S1)C(C(F)(F)F)C(F)(F)F
Targets
P49768PSEN1Q92542NCSTNQ9NZ42PSENENQ8WW43APH1BQ96BI3APH1A

What you can answer from here — as of January 29, 2025

5Protein targetsEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Begacestat, and which of those have an active Phase 3 trial?

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