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Neflamapimod
go.drugbank.com/drugs/DB07138InvestigationalNeflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.
Sifalimumab
go.drugbank.com/drugs/DB12773InvestigationalSifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients. … The levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disease activity.
Ganulameran
go.drugbank.com/drugs/DB16442InvestigationalAs such, BNT162b3 has entered a phase I/II study in early September 2020 (NCT04537949). … Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it.
Relutrigine
go.drugbank.com/drugs/DB21614InvestigationalThe usage of the INN stem '-trigine' in the name indicates that Relutrigine is a sodium channel blocker, signal transduction modulator. … Relutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
go.drugbank.com/drugs/DB08398InvestigationalPhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
REP8839
go.drugbank.com/drugs/DB05224ExperimentalREP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Furafylline
go.drugbank.com/drugs/DB14029ExperimentalIt was developed on the context of asthma as a long-acting alternative for [theophylline].
HT-0712
go.drugbank.com/drugs/DB11650InvestigationalBLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Dactolisib
go.drugbank.com/drugs/DB11651InvestigationalDactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Figitumumab
go.drugbank.com/drugs/DB11685InvestigationalFigitumumab has been used in trials studying the treatment of Sarcoma, Solid Tumor, Breast Cancer, Lung Neoplasms, and Advanced Cancer, among others.