Neflamapimod

DB07138InvestigationalSmall molecule

Neflamapimod has been used in trials studying the treatment of Alzheimer's Disease and Mild Cognitive Impairment.

Chemical structure of Neflamapimod
Mechanism
Curator reviewed
Formula / weight
C19H9Cl2F2N3OS · 436.262 g/mol (avg)
Code names
VD-31,745 · VRT-031745 · VX-745

Resolves to

Compound
UNIITYL52QM320CAS209410-46-8ChEMBLCHEMBL119385ChEBI90528PubChem3038525
Structure
InChIKeyVEPKQEUBKLEPRA-UHFFFAOYSA-NSMILESFC1=CC(F)=C(SC2=NN3C=NC(=O)C(=C3C=C2)C2=C(Cl)C=CC=C2Cl)C=C1
Targets
Q16539MAPK14Q15759MAPK11P53778MAPK12

What you can answer from here — as of January 29, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
7Clinical trialsPhase, status and sponsor resolved per trial
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14+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Neflamapimod, and which of those have an active Phase 3 trial?

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