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Displaying results 881 - 890 of 10000 in total

Target
Matrix metalloproteinase-20
go.drugbank.com/bio_entities/BE0003696
TargetHumans
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role i...
Polypeptides: Matrix metalloproteinase-20Synonyms: MMP-20
Drug
Repaglinide
go.drugbank.com/drugs/DB00912
ApprovedInvestigational
In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control … Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine.
Mixtures: PAREGLIN 1 MG/500 MG FILM KAPLI TABLET, 90 ADET, PAREGLIN 2 MG/500 MG FILM KAPLI TABLET, 90 ADETCategories: Heterocyclic Compounds, 1-Ring
Drug
Teriparatide
go.drugbank.com/drugs/DB06285
ApprovedInvestigational
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Eu...
Synonyms: PTH 1-34, PTH (1-34)Products: FORTEO INJECTION 20 mcg/80mcL, FORSTEO 20 MCG/80 MCL KULLANIMA HAZIR DOLU ENJEKSIYON KALEMI ICINDE COZELTI, 2.4 ML
Drug
Etilefrine
go.drugbank.com/drugs/DB08985
ApprovedWithdrawn
Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Adrenergic beta-1 Receptor AgonistsProducts: ETILEFRINACLORHIDRATO 10 MG /ML, ETILEFRINA CLORHIDRATO 10 MG/ ML
Drug
Perindopril
go.drugbank.com/drugs/DB00790
ApprovedInvestigational
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Mixtures: Triveram 20 mg/10 mg/10 mg Filmtabletten, TRIVERAM FILM-COATED TABLET 20 mg/10 mg/10 mgCategories: Heterocyclic Compounds, 2-Ring
Drug
Sodium aurothiomalate
go.drugbank.com/drugs/DB09276
ApprovedWithdrawn
Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Products: MYOCRISIN INJECTION 20 MG (4% W/V), MIOCRIN 50 MG
Drug
Pioglitazone
go.drugbank.com/drugs/DB01132
ApprovedInvestigational
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis.
Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Heterocyclic Compounds, 1-Ring
Drug
Alogliptin
go.drugbank.com/drugs/DB06203
ApprovedInvestigational
FDA approved January 25, 2013. … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Heterocyclic Compounds, 1-Ring
Drug
Ferrous fumarate
go.drugbank.com/drugs/DB14491
ApprovedInvestigational
Used in treatment of iron deficiency anemia.
Mixtures: Vitamin C 202,8 mg/0,8 mg/100 mg - Hartkapseln, VemaVite-PRx 2 with Fish-Based DHASynonyms: Iron(2+) fumarate
Drug
Deoxycholic acid
go.drugbank.com/drugs/DB03619
ApprovedInvestigational
In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity.
Synonyms: (3α,5β,12α)-3,12-dihydroxycholan-24-oic acidProducts: BELKYRA INJECTION 10 MG/ML, Belkyra 10 mg/ml Injektionslösung