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Displaying results 881 - 890 of 10000 in total
  1. Drug

    (4'-{[Allyl(Methyl)Amino]Methyl}-1,1'-Biphenyl-4-Yl)(4-Bromophenyl)Methanone

    go.drugbank.com/drugs/DB03234
    Experimental

    Synonyms: (4'-{[Allyl(Methyl)Amino]Methyl}-1,1'-Biphenyl-4-Yl)(4-Bromophenyl)Methanone
  2. Drug

    4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile

    go.drugbank.com/drugs/DB07002
    Experimental

    Synonyms: 4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile
  3. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

    Synonyms: 3,3-Bis(4-hydroxyphenyl)phthalideInternational brands: Feen-a-mint gum, Feen-a-mint laxative mints
  4. Drug

    Alectinib

    go.drugbank.com/drugs/DB11363
    ApprovedInvestigational

    Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. … It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC

    Synonyms: 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitors
  5. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. … In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent

    Synonyms: 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, (±)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylateInternational brands: Felodur ER, Plendil ER
  6. Drug

    Glycerol phenylbutyrate

    go.drugbank.com/drugs/DB08909
    ApprovedInvestigational

    Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

    Synonyms: Glyceryl Tri-4-PhenylbutyrateCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2D6 Inhibitors
  7. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [A275508] Specifically, vepdegestrant is being developed as a first-line or subsequent treatment option for patients whose tumors grow in response to estrogen and have progressed after standard therapies … , such as cyclin-dependent kinase (CDK) 4/6 inhibitors.

    Synonyms: 2,6-piperidinedione, 3-(1,3-dihydro-1-oxo-5-(4-((1-(4-((1r,2s)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl)phenyl)-4-piperidinyl)methyl)-1-piperazinyl)-2h-isoindol-2-yl)-, (3s)-Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 Inhibitors
  8. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall

    Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineMixtures: M-FURO MANT % 0.1 + % 1 KREM, 20G, Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%
  9. Drug

    Besigomsin

    go.drugbank.com/drugs/DB20894
    Experimental

    Besigomsin is a small molecule drug. Besigomsin has a monoisotopic molecular weight of 416.18 Da.

    Synonyms: Gomisin a, (+)-gomisin aCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  10. Drug

    (2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine

    go.drugbank.com/drugs/DB07857
    Experimental

    Synonyms: (2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine