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Displaying results 881 - 890 of 1994 in total
  1. Drug

    Flumazenil

    go.drugbank.com/drugs/DB01205
    ApprovedInvestigational

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine

  2. Indication

    Letterer-Siwe disease

    go.drugbank.com/conditions/DBCOND0021755
    Drugs: Vinblastine
    Synonyms: Letterer-Siwe disease of unspecified sites (disorder), Letterer-Siwe disease
  3. Drug

    Elvitegravir

    go.drugbank.com/drugs/DB09101
    ApprovedInvestigational

    Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral ...

    Mixtures: GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADET, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADET
  4. Target

    POU domain, class 2, transcription factor 2

    go.drugbank.com/bio_entities/BE0004865
    EnzymeTransporterHumans

    Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addi...

    Polypeptides: POU domain, class 2, transcription factor 2
  5. Target

    POU domain, class 2, transcription factor 1

    go.drugbank.com/bio_entities/BE0009712
    TransporterHumans

    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription tr...

    Polypeptides: POU domain, class 2, transcription factor 1
  6. Drug

    Gallium citrate Ga-67

    go.drugbank.com/drugs/DB06784
    Approved

    Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation

  7. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after

    Mixtures: ISICOM 100MG/25MG, ISICOM 100MG/25MG
  8. Drug

    Infigratinib

    go.drugbank.com/drugs/DB11886
    ApprovedInvestigationalWithdrawn

    [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR receptor subtypes.

  9. Indication

    Haemophilus Influenzae Infections

    go.drugbank.com/conditions/DBCOND0042753
    Drugs: Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
    Synonyms: Hemophilus influenzae infection, unspecified site
  10. Indication

    Oral Candidiasis

    go.drugbank.com/conditions/DBCOND0028285
    Drugs: Dequalinium ยท Nystatin
    Synonyms: Candidiasis of unspecified site