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Naquotinib
go.drugbank.com/drugs/DB12036InvestigationalNaquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth
Ibuzatrelvir
go.drugbank.com/drugs/DB19451InvestigationalIbuzatrelvir is under investigation in clinical trial NCT06679140 (A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized but
SIG-207
go.drugbank.com/drugs/DB18547ExperimentalSIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified
CDX-1135
go.drugbank.com/drugs/DB17607InvestigationalCDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).
2'-fluoro-5-ethylarabinosyluracil
go.drugbank.com/drugs/DB13030Investigational2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma
Lutetium Lu-177 DOTA-ABM-5G
go.drugbank.com/drugs/DB33946ExperimentalLutetium Lu-177 DOTA-ABM-5G is under investigation in clinical trial NCT06389123 (Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas).
FP0011
go.drugbank.com/drugs/DB05090ExperimentalIt acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.
VH3739937
go.drugbank.com/drugs/DB25287InvestigationalVH3739937 is under investigation in clinical trial NCT06533280 (VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect (FE
Alvocidib
go.drugbank.com/drugs/DB03496InvestigationalAlvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer.
D2C7 immunotoxin
go.drugbank.com/drugs/DB17540InvestigationalD2C7 immunotoxin (D2C7-IT) is an investigational dual-specific monoclonal antibody targeting EGFRwt and EGFRvIII with a genetically engineered form of the _Pseudomonas exotoxin_, PE38-KDEL.