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Displaying results 8921 - 8930 of 10000 in total
  1. Drug

    Factor XIII (human)

    go.drugbank.com/drugs/DB12909
    ApprovedInvestigational

    Within the body, FXIII circulates as a heterotetramer composed of 2 A-subunits and 2 B-subunits (A2B2)[A32363]. … As the half-life of endogenous Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4-6 to maintain hemostasis[A32363].

    International brands: Fibrogammin P
  2. Drug

    Bimekizumab

    go.drugbank.com/drugs/DB12917
    ApprovedInvestigational

    Bimekizumab is a humanized monoclonal antibody directed towards IL-17, which was approved for use in the EU on August 20, 2021, for the treatment of plaque psoriasis. … [A244455] It has demonstrated superior efficacy as compared to another IL-17 inhibitor, [secukinumab], as well as [ustekinumab] (an IL-12/23 inhibitor) and [adalimumab] (a TNF inhibitor) in the treatment

  3. Drug

    T-62

    go.drugbank.com/drugs/DB12919
    Investigational

    T-62 has been used in trials studying the treatment of Postherpetic Neuralgia.

    Synonyms: T-62
  4. Drug

    Opipramol

    go.drugbank.com/drugs/DB12930
    Investigational

    Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

    Categories: Heterocyclic Compounds, 3-Ring
  5. Drug

    Quercetin-3'-O-phosphate

    go.drugbank.com/drugs/DB12937
    Investigational

    Quercetin-3'-O-phosphate has been used in trials studying the treatment of Insulin Resistance and Impaired Glucose Tolerance.

  6. Drug

    Darolutamide

    go.drugbank.com/drugs/DB12941
    ApprovedInvestigational

    Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC).

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    5-fluoro-2'-deoxycytidine

    go.drugbank.com/drugs/DB12957
    Investigational

    5-fluoro-2'-deoxycytidine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, and Urinary Bladder Neoplasms, among others.

    Synonyms: 5-fluoro-2-deoxycytidine, 5-fluoro-2'-deoxycytidineCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    IOWH-032

    go.drugbank.com/drugs/DB12959
    Investigational

    Iowh032 has been investigated for the treatment of Cholera, Diarrhea, and Secretory Diarrhea.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Serlopitant

    go.drugbank.com/drugs/DB12973
    Investigational

    Serlopitant has been investigated for the treatment of Prurigo Nodularis.

    Categories: Heterocyclic Compounds, 2-Ring, Neurokinin-1 Receptor Antagonists
  10. Drug

    Nepicastat

    go.drugbank.com/drugs/DB12979
    Investigational

    Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.

    Synonyms: (S)-5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring