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Displaying results 8921 - 8930 of 10000 in total
  1. Drug

    RST-001

    go.drugbank.com/drugs/DB17843
    Investigational

    RST-001 is a non-replicating recombinant adeno-associated virus vector containing a fragment of the gene encoding channel rhodopsin-2 protein.

  2. Drug

    Licaminlimab

    go.drugbank.com/drugs/DB18936
    Investigational

    Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease).

    Synonyms: immunoglobulin scFv, anti-[Homo sapiens TNF (tumor necrosis factor, TNFSF2, DIF, TNF-alpha)], humanized monoclonal antibody single chain; IG scFv humanized single chain (V-KAPPA-VH) (1-254) [V-KAPPA (Homo, sapiens IGKV1-5*03 (79.2%) -(IGHD) -IGKJ2*02 (77.
  3. Drug

    Eltrekibart

    go.drugbank.com/drugs/DB19017
    Investigational

    Eltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).

  4. Drug

    Sodium copper chlorophyllin

    go.drugbank.com/drugs/DB16522
    Investigational

    SCC of the commercial-grade is prepared from a reaction between a crude chlorophyll extract and methanolic sodium hydroxide, followed by replacement of the central magnesium atom with a heavy metal[A227718 … This compound is used as a food colorant and supplement[A227718].

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings
  5. Drug

    Dovitinib

    go.drugbank.com/drugs/DB05928
    Investigational

    Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. … Chiron currently has three ongoing Phase I clinical trials for dovitinib.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 Inducers
  6. Drug

    Pipendoxifene

    go.drugbank.com/drugs/DB05414
    Investigational

    ER modulator, ERA-923(Pipendoxifene) is a estrogen receptor modulator being evaluated for the treatment of breast cancer. … Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an excellent preclinical pharmacological profile and was selected for further development as a treatment

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Veltuzumab

    go.drugbank.com/drugs/DB05656
    Investigational

    Veltuzumab is a monoclonal antibody which, as of October 2009, is undergoing Phase I/II clinical trials for the treatment of non-Hodgkin's lymphoma.

  8. Drug

    Mitumomab

    go.drugbank.com/drugs/DB06462
    Experimental

    Mitumomab, an anti-BEC-2 monoclonal antibody derived from mice, was previously studied to treat small cell lung carcinoma in combination with BCG vaccination.

  9. Drug

    Mipsagargin

    go.drugbank.com/drugs/DB11813
    Investigational

    Mipsagargin has been used in trials studying the treatment of Prostate Cancer, Prostatic Neoplasms, Advanced Solid Tumors, Glioblastoma Multiforme, and Hepatocellular Carcinoma, among others.

  10. Drug

    BQ-123

    go.drugbank.com/drugs/DB12054
    Investigational

    BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.