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Tovinontrine
go.drugbank.com/drugs/DB16193InvestigationalTovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. … Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Synonyms: 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A)PYRAZIN-8(7H)-ONE, 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin-8-oneTBX-3400
go.drugbank.com/drugs/DB17370InvestigationalTBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.
Enbucrilate
go.drugbank.com/drugs/DB12358InvestigationalEnbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).
Cicletanine
go.drugbank.com/drugs/DB12766InvestigationalCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
Terpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Farampator
go.drugbank.com/drugs/DB15012InvestigationalFarampator is under investigation in clinical trial NCT00113022 (Org 24448 to Treat Major Depression).
Fluciclovine
go.drugbank.com/drugs/DB15237InvestigationalFluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Idursulfase beta
go.drugbank.com/drugs/DB16190InvestigationalIdursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Onfekafusp alfa
go.drugbank.com/drugs/DB16269InvestigationalOnfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
TPCA-1
go.drugbank.com/drugs/DB17058ExperimentalTPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]