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Paxalisib
go.drugbank.com/drugs/DB15186InvestigationalGDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Synonyms: 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amineMEDI6012
go.drugbank.com/drugs/DB14833InvestigationalRecombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction
BMS-986141
go.drugbank.com/drugs/DB14942InvestigationalBMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
IO-202
go.drugbank.com/drugs/DB17548InvestigationalIO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.
V116517
go.drugbank.com/drugs/DB16060InvestigationalV116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
Befiradol
go.drugbank.com/drugs/DB19033InvestigationalBefiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia).
Bleomycin A2
go.drugbank.com/drugs/DB19091InvestigationalBleomycin A2 is under investigation in clinical trial NCT00026208 (Combination Chemotherapy Plus Low-dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma).
Hemoglobin glutamer-250 (bovine)
go.drugbank.com/drugs/DB19235InvestigationalHemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).
Rhenium re-188
go.drugbank.com/drugs/DB19267InvestigationalRhenium re-188 is under investigation in clinical trial NCT03458559 (Rhenium-188-hedp vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy).
Surovatamig
go.drugbank.com/drugs/DB19420InvestigationalTNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).
Synonyms: H-gamma4 heavy chain anti-CD3D/CD3E dimer, Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (100%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG4*01 nG4m(a)