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Displaying results 8971 - 8980 of 10000 in total
  1. Drug

    IN01

    go.drugbank.com/drugs/DB16434
    Experimental

    Of note, the IN01 vaccine is being tested in a Phase I clinical trial in patients with fibrosing interstitial lung disease resulting from SARS-CoV-2 infection (NCT04537130). … The study will explore the effect of this vaccine on pulmonary function, oxygen saturation, quality of life, and fibrosing status in addition to biomarkers and molecular markers of the vaccine.

  2. Drug

    Ceforanide

    go.drugbank.com/drugs/DB00923
    Approved

    Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. … Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms.

  3. Drug

    Fluorfenidine F-18

    go.drugbank.com/drugs/DB19557
    Experimental

    Fluorfenidine F-18 is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Fluorfenidine F-18 is a a2 adrenoreceptor agonist.

  4. Drug

    VPM1002

    go.drugbank.com/drugs/DB15801
    Investigational

    This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults through post-exposure immunization. … VPM1002 is a recombinant BCG vaccine candidate expressing listeriolysin and deficient in urease that is generated in the genetic background of BCG Prague as it has a better safety profile than some other

  5. Drug

    VH3739937

    go.drugbank.com/drugs/DB25287
    Investigational

    VH3739937 is under investigation in clinical trial NCT06533280 (VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect … VH3739937 is a small molecule drug.

  6. Drug

    Tanogitran

    go.drugbank.com/drugs/DB21367
    Investigational

    Tanogitran is under investigation in clinical trial NCT02254057 (Tolerability and Pharmacokinetics/-Dynamics of Single Rising Doses BIBT 986 BS in Healthy Male Subjects). … Tanogitran is a small molecule drug.

  7. Drug

    Rosabulin

    go.drugbank.com/drugs/DB20161
    Investigational

    Rosabulin is a small molecule drug. Rosabulin is under investigation in clinical trial NCT00276913 (A Phase I Study of STA-5312 in Subjects With Advanced or Metastatic Solid Tumors).

  8. Drug

    Crelosidenib

    go.drugbank.com/drugs/DB21642
    Investigational

    Crelosidenib is under investigation in clinical trial NCT04603001 (Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations). … Crelosidenib is a small molecule drug.

  9. Drug

    GLPG-0492

    go.drugbank.com/drugs/DB12461
    Investigational

    Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).

  10. Drug

    CM-4307

    go.drugbank.com/drugs/DB15414
    Investigational

    CM-4307 is under investigation in clinical trial NCT03602495 (Donafenib in 131I-Refractory Differentiated Thyroid Cancer).