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IMMU-114
go.drugbank.com/drugs/DB18458InvestigationalIMMU-114 is antibody-drug conjugate consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a CL2A linker.
Eftansomatropin alfa
go.drugbank.com/drugs/DB18460InvestigationalEftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment.
Esuberaprost
go.drugbank.com/drugs/DB18464InvestigationalEsuberaprost (GP-1681), a drug intended for participants with pulmonary arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and safety.
Synonyms: (+)-4-((1r,2r,3as,8bs)-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid, 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-1-octen-6-ynyl)-, (1r,2r,3as,8bs)-Spevatamig
go.drugbank.com/drugs/DB18471InvestigationalPT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47)
PT217
go.drugbank.com/drugs/DB18472InvestigationalPT217 is a bispecific Antibody against DLL3 and CD47
ASP-2138
go.drugbank.com/drugs/DB18473InvestigationalASP-2138 is a bispecific antibody directed against CLDN18.2 and T cell receptor complex CD3
VBI-1901
go.drugbank.com/drugs/DB18476InvestigationalVBI-1901 is a bivalent cytomeglaovirus gB/pp65 enveloped virus-like particles
Rodatristat
go.drugbank.com/drugs/DB18478ExperimentalSynonyms: (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)-4-pyrimidinyl)-2,8-diazaspiro(4.5)decane-3-carboxylic acid, (3s)-8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylic acidCategories: Heterocyclic Compounds, 1-RingHeparan-N-sulfatase (human, recombinant)
go.drugbank.com/drugs/DB18483InvestigationalRecombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Synonyms: Recombinant human heparan-N-sulfatase, Heparan-N-sulfatase (human, recombinant)ALT-P1
go.drugbank.com/drugs/DB18485InvestigationalALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.