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Afamitresgene autoleucel
go.drugbank.com/drugs/DB18592ApprovedInvestigational[L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved. … Afamitresgene autoleucel is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy product consisting of CD4 and CD8 positive T cells transduced with a
Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE, HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, A2-O, 3-O desulfated heparin
go.drugbank.com/drugs/DB17569InvestigationalSynonyms: 2-O, 3-O desulfated heparinRomilkimab
go.drugbank.com/drugs/DB16318InvestigationalRomilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)Radotermin
go.drugbank.com/drugs/DB19127InvestigationalRadotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the … Treatment of Early Stage Lumbar Disc Degeneration).
Synonyms: Recombinant human growth and differentiation factor-5, Growth differentiation factor 5 (human), homodimerNedaplatin
go.drugbank.com/drugs/DB13145ApprovedInvestigationalNedaplatin is a second generation platinum analog [A20300]. It is less nephrotoxic than [DB00515] but has proven equally effective. It was approved for use in Japan in 1995.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSynonyms: (glycolato-O,O')diammineplatinum(II)Clotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedThe minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].
Mixtures: Mecort C (Clotrimazole and Hydrocortisone Acetate Cream), Clotrimazole and Betamethasone DipropionateCategories: Imidazole and Triazole Derivatives, Gynecological Antiinfectives and AntisepticsHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica, Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone AcetateCategories: Hydrocortisone and derivatives, Hormones, Hormone Substitutes, and Hormone AntagonistsMucor circinelloides f. circinelloides
go.drugbank.com/drugs/DB15512ApprovedMucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, mucor circinelloides f. circinelloides, Mucor circinelloides f. circinelloidesProducts: Mucor circinelloides f. circinelloidesAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. … This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label].
Synonyms: o-acetoxybenzoic acid, O-acetylsalicylic acidMixtures: Ac and C Tab 1/8gr, Ache and Pain Relief to Go6-O-benzylguanine
go.drugbank.com/drugs/DB11919Investigational6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: O(6)-Benzylguanine, O6-benzylguanine