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Doxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generatio...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: DOXY - CT 200MG TABLETTEN, DOXY DENK 100MG TABLETTENDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnA cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Digimerck 0,07 mg - Tabletten, Digimerck 0,1 mg - TablettenPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigational[FDA Label] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: @ctavis 20 mg magensaftresistente Tabletten, @ctavis 40 mg magensaftresistente TablettenTolvaptan
go.drugbank.com/drugs/DB06212ApprovedInvestigationalTolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Tolvaptan ratiopharm 15 mg Tabletten, Tolvaptan ratiopharm 30 mg TablettenMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigationalMycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Myfortic 180 mg - magensaftresistente Tabletten, Myfortic 360 mg - magensaftresistente TablettenMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalMethadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorp...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Methasan 5 mg-Tabletten, Methasan 10 mg-TablettenFludarabine
go.drugbank.com/drugs/DB01073ApprovedInvestigationalFludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Products: Neoflubin 25 mg/ml Konzentrat zur Herstellung einer Injektions- oder Infusionslösung, Fludarabin Accord 25 mg/ml Konzentrat zur Herstellung einer Injektions- oder InfusionslösungAmisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalAmisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. As an antipsychotic agent, amisulpride alleviates both positive and negative symptoms of schizophrenia, and ...
Categories: P-glycoprotein substratesProducts: Amisu 50 mg-Tabletten, Amisu 100 mg-TablettenIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIsosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. Isosorbid...
Products: ISMN ABZ 20MG TABLETTEN, ISMN ABZ 40MG TABLETTENBethanechol
go.drugbank.com/drugs/DB01019ApprovedBethanechol is a synthetic ester that was initially synthesized in 1935. As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the para...
Products: Myocholine - Glenwood Tabletten 10 mg, Myocholine - Glenwood Tabletten 25 mg