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Methotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigationalMethotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate i...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: EMTHEXATE PF, EMTHEXATE PF 25 MG/MLAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: AMIODARONE PH&TAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 2...
Products: PP Alfa-DOL 1.00 mcg CapsuleCyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedCyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Cyclosporine/Chondroitin PF, Cyclosporine/Chondroitin Sulfate PFCyanocobalamin
go.drugbank.com/drugs/DB00115ApprovedInvestigationalNutraceuticalCyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis a...
Mixtures: Virt-Pn, Virt-PNProducts: Rubramin PCHydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalHydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It...
Synonyms: p-Benzenediol, p-HydroquinoneProducts: Aclaro PD Hydroquinone, Pa Plus Advanced Dark Spot Correcting SerumTiamulin
go.drugbank.com/drugs/DB11468ExperimentalVet approvedTiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2E1 InhibitorsProducts: PF TIAMULIN PREMIX 10% W/W POWDERSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalSimvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk o...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SIMVASTATIN Q-PH 10MG FTA, SIMVASTATIN Q-PH 20MG FTALevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigationalMenthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-oc...
Mixtures: Sarna P, PM ExternalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Products: LIPONSAEURE RATIO 600MG PI