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Displaying results 81 - 90 of 10000 in total
  1. Drug

    Teprotumumab

    go.drugbank.com/drugs/DB06343
    ApprovedInvestigational

    approved by the FDA in January 2020 for the treatment of TED. … [L11359] Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and was

    Synonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerCategories: Insulin-like Growth Factor-1 Receptor Inhibitor
  2. Drug

    Iodine I-131 monoclonal antibody 81C6

    go.drugbank.com/drugs/DB16197
    Investigational

    Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).

    Synonyms: Moab, 81c6, murine, iodine-I-131 radiolabeled, to human glioma, Iodine i 131 moab 81c6
  3. Drug

    123I-iodometomidate

    go.drugbank.com/drugs/DB13021
    Investigational

    123I-iodometomidate is under investigation in clinical trial NCT00454103 (Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy).

    Synonyms: 123 I Iodometomidate
  4. Drug

    Cerliponase alfa

    go.drugbank.com/drugs/DB13173
    ApprovedInvestigational

    [L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19, 2018. … [L51329] CLN2 is a predominantly pediatric-onset neurodegenerative disease caused by a deficiency in the lysosomal enzyme TPP1, leading to progressive impairment in motor and cognitive function.

    Categories: Hydrolytic Lysosomal N-terminal Tripeptidyl PeptidaseSynonyms: Immature tripeptidyl-peptidase I, Immature human tripeptidyl-peptidase 1
  5. Drug

    Tricarbonyl(1,10-phenanthroline)rhenium(1+)

    go.drugbank.com/drugs/DB04100
    Experimental

    Synonyms: tricarbonyl(1,10-phenanthroline)rhenium(I), (1,10 phenanthroline)-(tri-carbon monoxide) rhenium (I)
  6. Drug

    Iodine (131I) norcholesterol

    go.drugbank.com/drugs/DB13487
    Investigational

    Synonyms: Norcholestenol iodomethyl i-131
  7. Drug

    CER-001

    go.drugbank.com/drugs/DB18538
    Investigational

    CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. … [L48290] It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.

    Synonyms: Recombinant human apolipoprotein A-I/phospholipid complexesCategories: Apolipoproteins A
  8. Drug

    Sonpiretigene isteparvovec

    go.drugbank.com/drugs/DB17844
    Investigational

    Developed by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP). … Sonpiretigene isteparvovec is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy.

    Synonyms: vMCO-I, VMCO-1
  9. Drug

    Nadide

    go.drugbank.com/drugs/DB14128
    Investigational

    A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. … It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Coenzyme I, Cozymase I
  10. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting