This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Hypochlorous acid
- DrugBank Accession Number
- DB14135
- Background
An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Hypochlorous acid (DB14135)
- Weight
- Average: 52.46
Monoisotopic: 51.971592361 - Chemical Formula
- ClHO
- Synonyms
- Chlor(I)-säure
- Chloranol
- Hydroxidochlorine
- Hypochlorige Säure
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image AbsoClean-S Sanitizing Mist Liquid 0.006 mg/1mL Topical KEWS CORPORATION 2020-04-30 Not applicable US 
Acid oxidation potential water disinfection wet towel Cloth 0.9 g/100g Topical Fuzhou Meimei Environmental Protection Technology Co.,Ltd. 2020-05-06 Not applicable US Aeidar Hand Disinfectant Liquid 0.15 g/500mL Extracorporeal Shanghai Yishu Biotechnology Co., Ltd. 2020-06-09 Not applicable US Air raid card Wash free disinfectant Liquid 12 mg/100mL Topical Jiangsu Manwei Pharmaceutical Co.,Ltd 2020-04-20 Not applicable US Air raid card Wash free disinfectant Liquid 12 mg/100mL Topical Jiangsu Manwei Pharmaceutical Co.,Ltd 2020-04-20 Not applicable US Aktive Multi Purpose Antibacterial Liquid 0.25 mg/100mg Topical Hall Global LLC 2020-03-30 Not applicable US All Clean Water Liquid 0.07 g/100mL Topical MISSIWOMAN COSMETIC 2020-06-25 Not applicable US Allvirusu Liquid 0.002 g/100mL Topical StarParks 2020-10-12 Not applicable US AN XIN Disinfectant Liquid 10 mg/50mL Topical Guangdong Fengneng Environmental Protection Technology Inc. 2020-06-19 Not applicable US Aqunova. Water Innovation Liquid 0.1 g/100mL Topical Agricultural Company Corporation, Inc 2020-09-12 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image BabyO2 Hypochlorous acid (65.8 mg/240mL) + Silver (48 mg/240mL) + Zinc (6 mg/240mL) Liquid Topical Oxigenesis, Inc. 2020-09-20 Not applicable US Beklyn Absolute Purifying Hand Gel Hypochlorous acid (0.024 g/300mL) + Titanium dioxide (0.03 g/300mL) Gel Topical MY Corp.,Ltd 2020-07-15 Not applicable US Beklyn Absolute Purifying Hand Gel Hypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL) Gel Topical MY Corp.,Ltd 2020-07-15 Not applicable US Beklyn Absolute Purifying Hand Gel Hypochlorous acid (0.0144 g/180mL) + Titanium dioxide (0.018 g/180mL) Gel Topical MY Corp.,Ltd 2020-09-02 Not applicable US Beklyn Absolute Purifying Hand Gel Hypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL) Gel Topical MY Corp.,Ltd 2020-09-02 Not applicable US Beklyn Absolute Purifying Hand Gel Refreshing Aloe 180ml Hypochlorous acid (0.0144 g/180mL) + Titanium dioxide (0.018 g/180mL) Gel Topical MY Corp.,Ltd 2020-09-02 Not applicable US Beklyn Absolute Purifying Hand Gel Refreshing Aloe 60ml Hypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL) Gel Topical MY Corp.,Ltd 2020-09-02 Not applicable US Beklyn Absolute Purifying-Spray Hypochlorous acid (0.024 g/300mL) + Titanium dioxide (0.03 g/300mL) Liquid Topical MY Corp.,Ltd 2020-07-15 Not applicable US Beklyn Absolute Purifying-Spray Hypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL) Liquid Topical MY Corp.,Ltd 2020-07-15 Not applicable US CLEN GERM KILLER-Spray Hypochlorous acid (0.04 g/500mL) + Titanium dioxide (0.05 g/500mL) Liquid Topical MY Corp.,Ltd 2020-07-15 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image AbsoClean-S Sanitizing Mist Hypochlorous acid (0.006 mg/1mL) Liquid Topical KEWS CORPORATION 2020-04-30 Not applicable US Acid oxidation potential water disinfection wet towel Hypochlorous acid (0.9 g/100g) Cloth Topical Fuzhou Meimei Environmental Protection Technology Co.,Ltd. 2020-05-06 Not applicable US Aeidar Hand Disinfectant Hypochlorous acid (0.15 g/500mL) Liquid Extracorporeal Shanghai Yishu Biotechnology Co., Ltd. 2020-06-09 Not applicable US Air raid card Wash free disinfectant Hypochlorous acid (12 mg/100mL) Liquid Topical Jiangsu Manwei Pharmaceutical Co.,Ltd 2020-04-20 Not applicable US Air raid card Wash free disinfectant Hypochlorous acid (12 mg/100mL) Liquid Topical Jiangsu Manwei Pharmaceutical Co.,Ltd 2020-04-20 Not applicable US Aktive Multi Purpose Antibacterial Hypochlorous acid (0.25 mg/100mg) Liquid Topical Hall Global LLC 2020-03-30 Not applicable US All Clean Water Hypochlorous acid (0.07 g/100mL) Liquid Topical MISSIWOMAN COSMETIC 2020-06-25 Not applicable US Allvirusu Hypochlorous acid (0.002 g/100mL) Liquid Topical StarParks 2020-10-12 Not applicable US AN XIN Disinfectant Hypochlorous acid (10 mg/50mL) Liquid Topical Guangdong Fengneng Environmental Protection Technology Inc. 2020-06-19 Not applicable US Aqunova. Water Innovation Hypochlorous acid (0.1 g/100mL) Liquid Topical Agricultural Company Corporation, Inc 2020-09-12 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 712K4CDC10
- CAS number
- 7790-92-3
- InChI Key
- QWPPOHNGKGFGJK-UHFFFAOYSA-N
- InChI
- InChI=1S/ClHO/c1-2/h2H
- IUPAC Name
- hypochlorous acid
- SMILES
- OCl
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0059650
- ChemSpider
- 22757
- 1483316
- ChEBI
- 24757
- ChEMBL
- CHEMBL1616046
- PDBe Ligand
- 8TR
- Wikipedia
- Hypochlorous_acid
- PDB Entries
- 5ydv
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Supportive Care Coronavirus Disease 2019 (COVID‑19) 1 4 Completed Treatment Complications; Cesarean Section / Postoperative Wound Infection / Satisfaction / Wound Breakdown / Wound Infections 1 4 Recruiting Treatment Ocular bacterial infections 1 3 Active Not Recruiting Prevention Bloodloss 1 3 Completed Prevention Cataracts / Endophthalmitis 1 2 Completed Treatment Hypochlorous Acid / Mouthwashes 1 2 Unknown Status Prevention Surgical Site Infections 1 2, 3 Withdrawn Prevention Coronavirus (SARS-CoV) / Coronavirus Disease 2019 (COVID‑19) / Viral Infections 1 1 Completed Prevention Irritation/Irritant 1 Not Available Completed Health Services Research Circumcision / Disinfection / Newborn; Infection 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Topical 0.006 mg/1mL Liquid Extracorporeal 0.15 g/500mL Liquid Topical 0.25 mg/100mg Liquid Topical 0.07 g/100mL Liquid Topical 10 mg/50mL Liquid Topical 0.1 g/100mL Liquid Extracorporeal 0.48 mg/60mL Gel Topical Liquid Topical 0.1 mg/100mL Solution Topical 0.046 g Liquid Topical 8 mg/100mL Liquid Topical 0.4 mg/1mL Liquid Topical 555 mg/5L Liquid Topical 665 mg/5L Liquid Topical 0.005 mg/100mL Liquid Topical 12 mg/100mL Liquid Oral 1 g/100mL Spray Topical 0.0035 g/100mL Liquid Topical 0.03 g/300mL Spray Topical 0.0001 g/1mL Liquid Topical 0.0032 g/100mL Liquid Extracorporeal 17.5 g/25L Liquid Topical 210 mg/300mL Liquid Topical 350 mg/500mL Liquid Topical 0.015 g/100mL Liquid Topical 0.1 mg/1mL Liquid Topical 0.1 g/1L Liquid Topical 1 mg/100mL Spray Topical 0.02 g/100g Liquid Extracorporeal 0.006 mg/60mL Liquid Extracorporeal 0.006 g/60mL Liquid Extracorporeal 0.05 g/500mL Liquid Extracorporeal 0.05 mg/500mL Liquid Extracorporeal 0.75 mg/5000mL Liquid Extracorporeal 0.75 g/5000mL Liquid Extracorporeal 0.075 mg/500mL Liquid Extracorporeal 0.075 g/500mL Patch Topical 0.5 g/100g Solution Topical 0.8 mg/1mg Solution Topical 0.8 1/1 Liquid Topical 0.4 g/500mL Liquid Topical 200 mg/1000mL Cloth Topical 0.9 g/100g Spray Topical 0.05 g/100mL Spray Topical 0.9 g/100mL Liquid Topical 20 mg/100mL Liquid Oral 3 g/100mL Spray Topical 0.00007 g/1mL Liquid Topical 0.01 g/100mL Gel Topical 0.0005 mg/100mL Liquid Extracorporeal 170 mg/1L Liquid Topical 2 mg/100mL Solution Topical 95 mg/100mL Liquid Topical 0.2 mg/1mL Spray Topical 0.009 g/300mL Liquid Topical 0.015 g/500mL Spray Topical 0.06 mg/1mL Spray Topical 0.06 mg/100mL Liquid Topical 0.2 g/1000mL Liquid Topical 12 mg/60mL Liquid Topical 0.8 mg/100mL Liquid Extracorporeal 0.1 mg/500mL Liquid Extracorporeal 100 mg/500mL Liquid Topical 0.007 mg/1mL Liquid Topical 0.01 kg/100L Liquid Topical 0.02 kg/100L Liquid Topical 0.4 mg/100mL Liquid Topical 10 mg/100mL Cloth Topical 0.89 g/251 Cloth Topical 0.89 g/301 Cloth Topical 0.93 g/301 Gel Topical 236.5 mg/946mL Liquid Topical 236.5 mg/946mL Liquid Topical 50 mg/500mL Liquid Topical 0.004 g/100mL Liquid Topical 0.00136 g/17mL Liquid Extracorporeal 60 mg/1L Solution Topical Liquid Topical 100 g/100mL Liquid Extracorporeal 75 mg/500mL Liquid Extracorporeal 9 mg/60mL Liquid Topical 0.002 g/100mL Liquid Extracorporeal 0.1 g/1L Gel Topical 0.015 g/100mL Gel Topical 0.072 g/480mL Gel Topical 0.000385 g/100mL Liquid Topical 0.000385 g/100mL Solution Buccal Spray Topical Spray Topical 0.01 g/100mL Liquid Topical 42.915 mg/500mL Liquid Topical 0.03 g/1L Spray Topical 0.003 g/100mL Spray Topical 0.008 g/0.008g Liquid Topical 0.006 g/100mL Liquid Extracorporeal 0.3 mg/100mL Liquid Extracorporeal 0.3 mg/100mg Spray Topical 0.4 g/100mL Liquid Topical 11.5 mg/100mL Liquid Topical 5 mg/100mL Liquid Topical 0.46 mg/1mL Liquid Topical 250 mg/1L Spray Topical 0.07 g/100mL Spray Topical 100 g/100mL Cloth Topical 5 g/100g Liquid Topical 0.001 g/100mL Liquid Topical 100 mg/100L Liquid Endotracheal 776.9 mg/1000mL Spray Topical 0.025 g/500mL Liquid Topical Liquid Topical 0.005 g/500mL Liquid Topical 0.003 g/100mL Liquid Topical 0.005 g/100mL Liquid Topical 29.1 mg/485mL Liquid Topical 6 mg/100mL Liquid Topical 0.008 g/100mL Spray Cutaneous 0.008 mg/100mL Liquid Dental 100 g/100mL Gel Topical 495 g/500mL Spray Topical 495 g/500mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 512.0 mg/mL ALOGPS logP -0.37 ALOGPS logP 0.32 Chemaxon logS 0.99 ALOGPS pKa (Strongest Acidic) 7.93 Chemaxon pKa (Strongest Basic) -5.9 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 8.7 m3·mol-1 Chemaxon Polarizability 3.49 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-5de344503979a4f5b010 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-5de344503979a4f5b010 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-5de344503979a4f5b010 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-f4c1e86745fdf19ff4df Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-f4c1e86745fdf19ff4df Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-9000000000-f4c1e86745fdf19ff4df
Drug created at June 27, 2018 16:53 / Updated at June 12, 2020 16:53