This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Hypochlorous acid
DrugBank Accession Number
DB14135
Background

An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 52.46
Monoisotopic: 51.971592361
Chemical Formula
ClHO
Synonyms
  • Chlor(I)-säure
  • Chloranol
  • Hydroxidochlorine
  • Hypochlorige Säure

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
AbsoClean-S Sanitizing MistLiquid0.006 mg/1mLTopicalKEWS CORPORATION2020-04-30Not applicableUS flag
Acid oxidation potential water disinfection wet towelCloth0.9 g/100gTopicalFuzhou Meimei Environmental Protection Technology Co.,Ltd.2020-05-06Not applicableUS flag
Aeidar Hand DisinfectantLiquid0.15 g/500mLExtracorporealShanghai Yishu Biotechnology Co., Ltd.2020-06-09Not applicableUS flag
Air raid card Wash free disinfectantLiquid12 mg/100mLTopicalJiangsu Manwei Pharmaceutical Co.,Ltd2020-04-20Not applicableUS flag
Air raid card Wash free disinfectantLiquid12 mg/100mLTopicalJiangsu Manwei Pharmaceutical Co.,Ltd2020-04-20Not applicableUS flag
Aktive Multi Purpose AntibacterialLiquid0.25 mg/100mgTopicalHall Global LLC2020-03-30Not applicableUS flag
All Clean WaterLiquid0.07 g/100mLTopicalMISSIWOMAN COSMETIC2020-06-25Not applicableUS flag
AllvirusuLiquid0.002 g/100mLTopicalStarParks2020-10-12Not applicableUS flag
AN XIN DisinfectantLiquid10 mg/50mLTopicalGuangdong Fengneng Environmental Protection Technology Inc.2020-06-19Not applicableUS flag
Aqunova. Water InnovationLiquid0.1 g/100mLTopicalAgricultural Company Corporation, Inc2020-09-12Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
BabyO2Hypochlorous acid (65.8 mg/240mL) + Silver (48 mg/240mL) + Zinc (6 mg/240mL)LiquidTopicalOxigenesis, Inc.2020-09-20Not applicableUS flag
Beklyn Absolute Purifying Hand GelHypochlorous acid (0.0144 g/180mL) + Titanium dioxide (0.018 g/180mL)GelTopicalMY Corp.,Ltd2020-09-02Not applicableUS flag
Beklyn Absolute Purifying Hand GelHypochlorous acid (0.024 g/300mL) + Titanium dioxide (0.03 g/300mL)GelTopicalMY Corp.,Ltd2020-07-15Not applicableUS flag
Beklyn Absolute Purifying Hand GelHypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL)GelTopicalMY Corp.,Ltd2020-07-15Not applicableUS flag
Beklyn Absolute Purifying Hand GelHypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL)GelTopicalMY Corp.,Ltd2020-09-02Not applicableUS flag
Beklyn Absolute Purifying Hand Gel Refreshing Aloe 180mlHypochlorous acid (0.0144 g/180mL) + Titanium dioxide (0.018 g/180mL)GelTopicalMY Corp.,Ltd2020-09-02Not applicableUS flag
Beklyn Absolute Purifying Hand Gel Refreshing Aloe 60mlHypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL)GelTopicalMY Corp.,Ltd2020-09-02Not applicableUS flag
Beklyn Absolute Purifying-SprayHypochlorous acid (0.024 g/300mL) + Titanium dioxide (0.03 g/300mL)LiquidTopicalMY Corp.,Ltd2020-07-15Not applicableUS flag
Beklyn Absolute Purifying-SprayHypochlorous acid (0.0048 g/60mL) + Titanium dioxide (0.006 g/60mL)LiquidTopicalMY Corp.,Ltd2020-07-15Not applicableUS flag
CLEN GERM KILLER-SprayHypochlorous acid (0.04 g/500mL) + Titanium dioxide (0.05 g/500mL)LiquidTopicalMY Corp.,Ltd2020-07-15Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
AbsoClean-S Sanitizing MistHypochlorous acid (0.006 mg/1mL)LiquidTopicalKEWS CORPORATION2020-04-30Not applicableUS flag
Acid oxidation potential water disinfection wet towelHypochlorous acid (0.9 g/100g)ClothTopicalFuzhou Meimei Environmental Protection Technology Co.,Ltd.2020-05-06Not applicableUS flag
Aeidar Hand DisinfectantHypochlorous acid (0.15 g/500mL)LiquidExtracorporealShanghai Yishu Biotechnology Co., Ltd.2020-06-09Not applicableUS flag
Air raid card Wash free disinfectantHypochlorous acid (12 mg/100mL)LiquidTopicalJiangsu Manwei Pharmaceutical Co.,Ltd2020-04-20Not applicableUS flag
Air raid card Wash free disinfectantHypochlorous acid (12 mg/100mL)LiquidTopicalJiangsu Manwei Pharmaceutical Co.,Ltd2020-04-20Not applicableUS flag
Aktive Multi Purpose AntibacterialHypochlorous acid (0.25 mg/100mg)LiquidTopicalHall Global LLC2020-03-30Not applicableUS flag
All Clean WaterHypochlorous acid (0.07 g/100mL)LiquidTopicalMISSIWOMAN COSMETIC2020-06-25Not applicableUS flag
AllvirusuHypochlorous acid (0.002 g/100mL)LiquidTopicalStarParks2020-10-12Not applicableUS flag
AN XIN DisinfectantHypochlorous acid (10 mg/50mL)LiquidTopicalGuangdong Fengneng Environmental Protection Technology Inc.2020-06-19Not applicableUS flag
Aqunova. Water InnovationHypochlorous acid (0.1 g/100mL)LiquidTopicalAgricultural Company Corporation, Inc2020-09-12Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
712K4CDC10
CAS number
7790-92-3
InChI Key
QWPPOHNGKGFGJK-UHFFFAOYSA-N
InChI
InChI=1S/ClHO/c1-2/h2H
IUPAC Name
hypochlorous acid
SMILES
OCl

References

General References
Not Available
Human Metabolome Database
HMDB0059650
ChemSpider
22757
RxNav
1483316
ChEBI
24757
ChEMBL
CHEMBL1616046
PDBe Ligand
8TR
Wikipedia
Hypochlorous_acid
PDB Entries
5ydv

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentComplications; Cesarean Section / Postoperative Wound Infection / Satisfaction / Wound Breakdown / Wound Infections1
4RecruitingTreatmentOcular bacterial infections1
3RecruitingPreventionCataracts / Endophthalmitis1
2CompletedTreatmentHypochlorous Acid / Mouthwashes1
2Unknown StatusPreventionSurgical Site Infections1
2, 3Not Yet RecruitingPreventionCoronavirus (SARS-CoV) / Coronavirus Disease 2019 (COVID‑19) / Viral Infections1
1CompletedPreventionIrritation/Irritant1
Not AvailableCompletedPreventionCatheter Related Infections / Catheters / Children, Only / Chlorhexidine Adverse Reaction / Cutaneous lesions / Disinfectant Dye Adverse Reaction / Nursing Caries1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidTopical0.006 mg/1mL
LiquidExtracorporeal0.15 g/500mL
LiquidTopical0.25 mg/100mg
LiquidTopical0.07 g/100mL
LiquidTopical10 mg/50mL
LiquidTopical0.1 g/100mL
LiquidExtracorporeal0.48 mg/60mL
GelTopical
LiquidTopical0.1 mg/100mL
SolutionTopical0.046 g
LiquidTopical8 mg/100mL
LiquidTopical0.4 mg/1mL
LiquidTopical555 mg/5L
LiquidTopical665 mg/5L
LiquidTopical0.005 mg/100mL
LiquidTopical12 mg/100mL
LiquidOral1 g/100mL
SprayTopical0.0035 g/100mL
LiquidTopical0.03 g/300mL
SprayTopical0.0001 g/1mL
LiquidTopical0.0032 g/100mL
LiquidExtracorporeal17.5 g/25L
LiquidTopical210 mg/300mL
LiquidTopical350 mg/500mL
LiquidTopical0.015 g/100mL
LiquidTopical0.1 g/1L
LiquidTopical0.1 mg/1mL
LiquidTopical1 mg/100mL
SprayTopical0.02 g/100g
LiquidExtracorporeal0.006 mg/60mL
LiquidExtracorporeal0.006 g/60mL
LiquidExtracorporeal0.05 g/500mL
LiquidExtracorporeal0.05 mg/500mL
LiquidExtracorporeal0.75 g/5000mL
LiquidExtracorporeal0.75 mg/5000mL
LiquidExtracorporeal0.075 mg/500mL
LiquidExtracorporeal0.075 g/500mL
PatchTopical0.5 g/100g
SolutionTopical0.8 1/1
LiquidTopical0.4 g/500mL
LiquidTopical200 mg/1000mL
ClothTopical0.9 g/100g
SprayTopical0.05 g/100mL
SprayTopical0.9 g/100mL
LiquidTopical20 mg/100mL
LiquidOral3 g/100mL
SprayTopical0.00007 g/1mL
LiquidTopical0.01 g/100mL
GelTopical0.0005 mg/100mL
LiquidExtracorporeal170 mg/1L
LiquidTopical2 mg/100mL
SolutionTopical95 mg/100mL
LiquidTopical0.2 mg/1mL
SprayTopical0.009 g/300mL
LiquidTopical0.015 g/500mL
SprayTopical0.06 mg/1mL
SprayTopical0.06 mg/100mL
LiquidTopical0.2 g/1000mL
LiquidTopical12 mg/60mL
LiquidTopical0.8 mg/100mL
LiquidExtracorporeal0.1 mg/500mL
LiquidExtracorporeal100 mg/500mL
LiquidTopical0.007 mg/1mL
LiquidTopical0.01 kg/100L
LiquidTopical0.02 kg/100L
LiquidTopical0.4 mg/100mL
LiquidTopical10 mg/100mL
ClothTopical0.89 g/301
ClothTopical0.89 g/251
ClothTopical0.93 g/301
GelTopical236.5 mg/946mL
LiquidTopical236.5 mg/946mL
LiquidTopical50 mg/500mL
LiquidTopical0.004 g/100mL
LiquidTopical0.00136 g/17mL
LiquidExtracorporeal60 mg/1L
SolutionTopical
LiquidTopical100 g/100mL
LiquidExtracorporeal75 mg/500mL
LiquidExtracorporeal9 mg/60mL
LiquidTopical0.002 g/100mL
LiquidExtracorporeal0.1 g/1L
GelTopical0.015 g/100mL
GelTopical0.072 g/480mL
SolutionBuccal
SprayTopical
SprayTopical0.01 g/100mL
LiquidTopical42.915 mg/500mL
LiquidTopical0.03 g/1L
SprayTopical0.003 g/100mL
SprayTopical0.008 g/0.008g
LiquidTopical0.006 g/100mL
LiquidExtracorporeal0.3 mg/100mg
LiquidExtracorporeal0.3 mg/100mL
SprayTopical0.4 g/100mL
LiquidTopical11.5 mg/100mL
LiquidTopical5 mg/100mL
LiquidTopical0.46 mg/1mL
LiquidTopical250 mg/1L
SprayTopical0.07 g/100mL
SprayTopical100 g/100mL
ClothTopical5 g/100g
LiquidTopical0.001 g/100mL
LiquidTopical100 mg/100L
LiquidEndotracheal776.9 mg/1000mL
SprayTopical0.025 g/500mL
LiquidTopical
LiquidTopical0.005 g/500mL
LiquidTopical0.003 g/100mL
LiquidTopical0.005 g/100mL
LiquidTopical29.1 mg/485mL
LiquidTopical6 mg/100mL
LiquidTopical0.008 g/100mL
LiquidDental100 g/100mL
GelTopical495 g/500mL
SprayTopical495 g/500mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility512.0 mg/mLALOGPS
logP-0.37ALOGPS
logP0.32ChemAxon
logS0.99ALOGPS
pKa (Strongest Acidic)7.93ChemAxon
pKa (Strongest Basic)-5.9ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area20.23 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity8.7 m3·mol-1ChemAxon
Polarizability3.49 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-5de344503979a4f5b010
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-5de344503979a4f5b010
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-5de344503979a4f5b010
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-f4c1e86745fdf19ff4df
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-f4c1e86745fdf19ff4df
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-9000000000-f4c1e86745fdf19ff4df

Drug created at June 27, 2018 16:53 / Updated at June 12, 2020 16:53