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Displaying results 81 - 90 of 7399 in total
  1. Drug

    Albusomatropin

    go.drugbank.com/drugs/DB12950
    Investigational

    Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.

    Synonyms: HUMAN SERUM ALBUMIN FUSED TO THE N-TERMINUS OF GROWTH HORMONE
  2. Drug

    AVID-200

    go.drugbank.com/drugs/DB18454
    Investigational

    AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.

    Synonyms: Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid-200)
  3. Drug

    Royal jelly

    go.drugbank.com/drugs/DB14250
    Investigational

    Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Honey Bee Secretion Used in the Nutrition of Larvae and Adult Queens Secreted From Worker Bee Hypopharyngeal Glands
  4. Drug

    Goflikicept

    go.drugbank.com/drugs/DB16396
    Investigational

    Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coron...

    Synonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein
  5. Drug

    Spanlecortemlocel

    go.drugbank.com/drugs/DB17130
    Investigational

    Synonyms: Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and CD34 depleted) derived from the same UCB unit
  6. Drug

    Coptisine

    go.drugbank.com/drugs/DB19308
    Experimental

    Synonyms: Alkaloid a, from coptis groenlandica
  7. Drug

    Orvacabtagene autoleucel

    go.drugbank.com/drugs/DB17231
    Investigational

    Synonyms: CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE SELF-INACTIVATING (SIN) LENTIVIRAL V, JCARH125 CONSISTS OF HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE THERAPY.
  8. Drug

    PRGN-3006

    go.drugbank.com/drugs/DB17229
    Investigational

    PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface

    Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surface, PRGN-3006 UltraCAR-T
  9. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    Developed by Sangamo Therapeutics, tefidsogene civaparvovec is being investigated in mucopolysaccharidosis type II.[A258789, L45949]

    Synonyms: NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM
  10. Drug

    Palopegteriparatide

    go.drugbank.com/drugs/DB18676
    ApprovedInvestigational

    [A264199] Upon administration, PTH is cleaved from palopegteriparatide in a controlled manner to achieve a continuous systemic exposure of active PTH. … [L51134] PTH(1-34) contains the N-terminal part of the endogenous PTH molecule.

    Synonyms: Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34, Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, ether with N-[[[2-[[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl]-2-methylalanyl-L-seryl-L-valyl-L-seryl-L-α-glutamyl-L-isole