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Displaying results 81 - 90 of 7901 in total
  1. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.

    Products: Ag-paroxetine, PAROXETIN ABZ 20MG
  2. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    [T28] Being a potent vasodilator, diltiazem is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties.

    Synonyms: (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate, Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-yl esterInternational brands: Incoril AP
  3. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.

    Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepineProducts: MIRTAZAPINA HEXAL AG, MIRTAZAPIN AL 15MG
  4. Drug

    Silodosin

    go.drugbank.com/drugs/DB06207
    ApprovedInvestigational

    Silodosin is available as oral capsules with common trade names Rapaflo and Urorec. It is indicated for the symptomatic treatment of benign prostatic hyperplasia in adults. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder

    Products: Ag-silodosin, SILODOSIN AL 4 MG HKP
  5. Drug

    Olanzapine

    go.drugbank.com/drugs/DB00334
    ApprovedInvestigational

    [A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring. … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.

    Synonyms: 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepineProducts: OLANZAPINA ABC, Ag-olanzapine Fc
  6. Drug

    Lansoprazole

    go.drugbank.com/drugs/DB00448
    ApprovedInvestigational

    Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)

    Mixtures: Aa-lansoprazole-amoxicillin-clarithromycinInternational brands: Zoprol
  7. Target

    Tyrosinase

    go.drugbank.com/bio_entities/BE0000252
    TargetEnzymeHumans

    This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production fro...

    Synonyms: LB24-AB, SK29-AB
  8. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone

    Products: Ag-finasteride, FINASTERIDE ABC
  9. Drug

    Quetiapine

    go.drugbank.com/drugs/DB01224
    ApprovedInvestigational

    It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment.

    Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolProducts: Ag-quetiapine, Ag-quetiapine XR
  10. Drug

    Anastrozole

    go.drugbank.com/drugs/DB01217
    ApprovedInvestigational

    as compared to earlier estrogen receptor modulators such as [tamoxifen]. … [L8863] Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and

    Products: Ag-anastrozole, Ag-anastrozole Tablets