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Displaying results 81 - 90 of 10000 in total
  1. Drug

    Obeticholic acid

    go.drugbank.com/drugs/DB05990
    ApprovedInvestigational

    [A18696] In 2016, it was granted approval to treat primary biliary cholangitis in combination with [ursodeoxycholic acid], which was previously the mainstay treatment for this condition. … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: (3α,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid
  2. Drug

    1alpha-Hydroxyvitamin D5

    go.drugbank.com/drugs/DB13097
    Investigational

    1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.

    Synonyms: 1alpha-Hydroxy-24-ethylcholecalciferol
  3. Drug

    N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide

    go.drugbank.com/drugs/DB01890
    Experimental

    Synonyms: D-Gluconamide, N,N'-((((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propanediyl)bis-, N,N'-((((3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propandiyl)bis-D-gluconamide
  4. Drug

    3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid

    go.drugbank.com/drugs/DB18044
    Experimental

    Synonyms: (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid, 3a,6b,7b,12a-(OH)4-5b-cholanic acid
  5. Drug

    Acrivastine

    go.drugbank.com/drugs/DB09488
    Approved

    As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension … Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.

    Mixtures: DUACT 8 MG/60 MG KAPSÜL, 30 ADETSynonyms: (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid
  6. Drug

    (S)-oct-1-en-3-ol

    go.drugbank.com/drugs/DB03025
    Experimental

    Synonyms: (S)-oct-1-en-3-ol
  7. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products. … Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the

    Mixtures: DESİFEROL PLUS 2000 IU+3333 IU+70 MG/ML ORAL DAMLA, 20 ML, COLEDAN-A 200.000IU/10 ML+100.000 IU/10 ML ORAL DAMLA, ÇÖZELTİ, 10 MLCategories: Retinoids for Topical Use in Acne, Compounds used in a research, industrial, or household setting
  8. Drug

    norUrsodeoxycholic acid

    go.drugbank.com/drugs/DB16260
    Investigational

    norUrsodeoxycholic acid is under investigation in clinical trial NCT03872921 (Norursodeoxycholic Acid vs Placebo in PSC).

    Synonyms: 24-norursodeoxycholic acid
  9. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men

    Categories: Prostaglandins E, Prostaglandin E1 AgonistSynonyms: (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, Prostaglandin E1
  10. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].

    Mixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%Categories: Cytochrome P-450 CYP2A6 Inducers, Cytochrome P-450 Substrates