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Insulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigationalMay 2024 for the same indication. … [L51078] In July 2024, the US FDA rejected the approval of insulin icodec, citing concerns regarding hypoglycemia and the indication being sought for type 1 diabetes mellitus.
Clostridium botulinum
go.drugbank.com/drugs/DB14223InvestigationalProducts: DYSPORT FOR INJECTION 500 u/vial, DYSPORT FOR INJECTION 300u/vialIohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chem...
Categories: Compounds used in a research, industrial, or household settingProducts: Hovid Iohexol Solution for Injection U.S.P. 300mg I/mL, Hovid Iohexol Solution for Injection U.S.P. 350mg I/mLXenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalThey undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal. … [A255183] In December 2022, the FDA approved the use of hyperpolarized Xe-129 for use with MRI for the evaluation of lung ventilation.
Sulbutiamine
go.drugbank.com/drugs/DB13416InvestigationalSulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer.
Products: NEURO UP® TABLETAS CUBIERTA CON PELICULA 200 MGHyaluronan mediated motility receptor
go.drugbank.com/bio_entities/BE0004702TargetHumansReceptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs.
Synonyms: Receptor for hyaluronan-mediated motilityCalcium-dependent secretion activator 1
go.drugbank.com/bio_entities/BE0008704TargetHumansCalcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading o...
Synonyms: Calcium-dependent activator protein for secretion 1(R)-carnitinyl-CoA betaine
go.drugbank.com/drugs/DB02516ExperimentalSynonyms: R-carnitinyl-CoA inner saltDipropylene glycol
go.drugbank.com/drugs/DB14140InvestigationalProducts: Abelia pomegranate bounce up maskCaplacizumab
go.drugbank.com/drugs/DB06081ApprovedInvestigational[A174634]In December 2025, the FDA expanded this indication to include pediatric patients aged 12 years and older with aTTP, in the same combination regimen.[L54958,L54963]