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Puromycin
go.drugbank.com/drugs/DB08437ExperimentalPuromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.
Palucorcel
go.drugbank.com/drugs/DB17955InvestigationalDeveloped by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Ripertamab
go.drugbank.com/drugs/DB16314InvestigationalRipertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated
Naquotinib
go.drugbank.com/drugs/DB12036InvestigationalNaquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth … Factor Receptor (EGFR) Mutations, among others.
Ibuzatrelvir
go.drugbank.com/drugs/DB19451InvestigationalIbuzatrelvir is under investigation in clinical trial NCT06679140 (A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized but
SIG-207
go.drugbank.com/drugs/DB18547ExperimentalSIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified
CDX-1135
go.drugbank.com/drugs/DB17607InvestigationalCDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).
2'-fluoro-5-ethylarabinosyluracil
go.drugbank.com/drugs/DB13030Investigational2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma
Lutetium Lu-177 DOTA-ABM-5G
go.drugbank.com/drugs/DB33946ExperimentalLutetium Lu-177 DOTA-ABM-5G is under investigation in clinical trial NCT06389123 (Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas).
FP0011
go.drugbank.com/drugs/DB05090ExperimentalIt acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.