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GLB-004
go.drugbank.com/drugs/DB32796ExperimentalGLB-004 is a molecular glue degrader targeting ARNT(HIF-1β).[L56125, L56126]
GLB-005
go.drugbank.com/drugs/DB32797ExperimentalGLB-005 is a molecular glue degrader targeting WIZ and is being investigated for treatment of sickle cell disease and β-thalassemia.[L56125, L56126, L56128]
GLB-007
go.drugbank.com/drugs/DB32798ExperimentalGLB-007 is a molecular glue degrader targeting WIZ and ZBTB7A.[L56125, L56126, L56128]
GLB-006
go.drugbank.com/drugs/DB32799ExperimentalGLB-006 is a molecular glue degrader targeting NEK7.[L56125, L56126]
APT20TTMG
go.drugbank.com/drugs/DB32869ExperimentalAPT20TTMG is a synthetic DNA that modulates U1 small nuclear ribonucleoprotein misassembly.
Reteplase
go.drugbank.com/drugs/DB00015ApprovedInvestigationalWithdrawnRetavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.
Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADETSargramostim
go.drugbank.com/drugs/DB00020ApprovedInvestigationalSargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.
Pegvisomant
go.drugbank.com/drugs/DB00082ApprovedInvestigationalPegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly.
Antithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. … Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.