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Displaying results 9041 - 9050 of 10000 in total
  1. Drug

    Dolcanatide

    go.drugbank.com/drugs/DB13112
    Investigational

    Dolcanatide has been investigated in Exposure.

  2. Drug

    N,N-dimethylarginine

    go.drugbank.com/drugs/DB01686
    Experimental

    ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. … It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid.

    Synonyms: N(5)-((Dimethylamino)iminomethyl)-L-ornithine, dimethyl-L-arginine
  3. Drug

    QRX-411

    go.drugbank.com/drugs/DB17868
    Experimental

    QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein. … It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777]

  4. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

    Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamine
  5. Drug

    SRD-001

    go.drugbank.com/drugs/DB25902
    Investigational

    SRD-001 is a biologic drug. … SRD-001 is under investigation in clinical trial NCT06224660 (Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy).

  6. Drug

    Drostanolone

    go.drugbank.com/drugs/DB00858
    ExperimentalIllicit

    Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy. … Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone.

  7. Drug

    LGD-6972

    go.drugbank.com/drugs/DB14779
    Investigational

    LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes

  8. Drug

    BN‐Brachyury vaccine

    go.drugbank.com/drugs/DB17425
    Experimental

    BN‐Brachyury vaccine is a novel prime‐boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)‐Brachyury booster vaccine.[A255173]

    Synonyms: BN‐Brachyury vaccine
  9. Drug

    MK-0773

    go.drugbank.com/drugs/DB16244
    Investigational

    MK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)).

  10. Drug

    Modakafusp alfa

    go.drugbank.com/drugs/DB16399
    Investigational

    Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory