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Oridonin
go.drugbank.com/drugs/DB19086InvestigationalOridonin is under investigation in clinical trial NCT05130892 (Effect of Inflammasome Inhibitor on Hscrp in Patients After PCI).
Synonyms: Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1.alpha.,6.beta.,7.alpha.,14r)-, Kaur-16-en-15-one, 7.alpha.,20-epoxy-1.alpha.,6.beta.,7,14-tetrahydroxy-, (14r)-Baxdrostat
go.drugbank.com/drugs/DB19090ApprovedInvestigationalOn May 18, 2026, baxdrostat was approved by the FDA as a first-in-class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive drugs [L56189]. … It targets aldosterone excess, a primary underlying driver of treatment resistance and organ damage in cardiovascular diseases [A275512, A275515].
Synonyms: (+)-(r)-n-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide, N-((8r)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl)propanamideCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesModified vaccinia virus Ankara-85A antigen
go.drugbank.com/drugs/DB19092InvestigationalModified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
SPH-3127
go.drugbank.com/drugs/DB19108InvestigationalSPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Synonyms: CARBAMIC ACID, N-(3-(3-((1R)-1-(CYCLOPROPYL((2R)-2-MORPHOLINYLCARBONYL)AMINO)ETHYL)-6-METHYL-1H-PYRAZOLO(3,4-B)PYRIDIN-1-YL)PROPYL)-, METHYL ESTERCategories: Heterocyclic Compounds, 1-RingIsuzinaxib
go.drugbank.com/drugs/DB19109InvestigationalIsuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).
Synonyms: 1-(pyridin-2-yl)-3-phenyl-4-propyl-1h-pyrazol-5-ol, 1h-pyrazol-5-ol, 3-phenyl-4-propyl-1-(2-pyridinyl)-Categories: Heterocyclic Compounds, 1-RingKER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Synonyms: QUINOLINE, 7-FLUORO-6-METHOXY-4-(6-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-Kisspeptin
go.drugbank.com/drugs/DB19112InvestigationalKisspeptin is under investigation in clinical trial NCT03315325 (Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men).
Synonyms: Kiss-1 metastasis suppressorTuparstobart
go.drugbank.com/drugs/DB19118Investigational≥ 1) Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck). … Tuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS
Synonyms: INCAGN02385 κ-chain, dimer, Anti-LAG-3 Monoclonal Antibody INCAGN02385Timbetasin
go.drugbank.com/drugs/DB19119InvestigationalTimbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Synonyms: N-ACETYL-L-SERYL-L-ASPARTYL-L-LYSYL-L-PROLYL-L-ASPARTYL-L-METHIONYL-L-ALANYL-L-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-ASPARTYL-L-LYSYL-L-SERYL-L-LYSYL-L-LEUCYL-L-LYSYL-L-LYSYL-L-THEONYL-L-GLUTAMYL-L-THEONYL-L-GLUTAMINYL-L-GLUTAMYL-L-LYS, L-SERINE, N-ACETYL-L-SERYL-L-.ALPHA.-ASPARTYL-L-LYSYL-L-PROLYL-L-.ALPHA.-ASPARTYL-L-METHIONYL-L-ALANYL-L-.ALPHA.-GLUTAMYL-L-ISOLEUCYL-L-.ALPHA.-GLUTAMYL-L-LYSYL-L-PHENYLALANYL-L-.ALPHA.Sotevtamab
go.drugbank.com/drugs/DB19120InvestigationalSotevtamab is under investigation in clinical trial NCT06225843 (Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis).
Synonyms: -chain) (human-mus musculus monoclonal ab-16b5 .gamma.2-chain), disulfide with human-mus musculus monoclonal ab-16b5 .kappa.-chain, dimer