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Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
CIGB-258 peptide
go.drugbank.com/drugs/DB15809ExperimentalAs of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens
Idetrexed
go.drugbank.com/drugs/DB21469InvestigationalThe usage of the INN stem '-trexed' in the name indicates that Idetrexed is a antineoplastic; thymidilate synthetase inhibitor. … Idetrexed is under investigation in clinical trial NCT02360345 (Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly). Idetrexed has a monoisotopic molecular weight of 647.22 Da.
AZD-9164
go.drugbank.com/drugs/DB12115InvestigationalAZD9164 has been used in trials studying the basic science and treatment of Chronic Obstructive Pulmonary Disease.
Dianicline
go.drugbank.com/drugs/DB12125InvestigationalDianicline has been used in trials studying the treatment of Smoking, Smoking Cessation, and Tobacco Use Cessation.
CP1-1189
go.drugbank.com/drugs/DB12311InvestigationalCPI-1189 has been used in trials studying the treatment of HIV Infections and AIDS Dementia Complex.
Toreforant
go.drugbank.com/drugs/DB12522InvestigationalToreforant has been used in trials studying the treatment of Asthma, Psoriasis, Hepatic Impairment, and Rheumatoid Arthritis.