7-beta-Hydroxyepiandrosterone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
7-beta-Hydroxyepiandrosterone
Accession Number
DB06622
Description
Not Available
Type
Small Molecule
Groups
Investigational
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Structure
Thumb
Weight
Average: 306.446
Monoisotopic: 306.219494826
Chemical Formula
C19H30O3
Synonyms
  • (3beta,5alpha,7beta)-3,7-Dihydroxyandrostan-17-one
  • 7beta-OH-Epia
  • 7β-Hydroxyepiandrosterone
  • 7β-OH-EPIA
External IDs
  • HF-0220
  • HF0220

Pharmacology

Indication

Investigated for use/treatment in alzheimer's disease.

Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified

Chemical Identifiers

UNII
OCP3E5KD08
CAS number
25848-69-5
InChI Key
VFPMCLQMAUVEHD-UCPSWNCLSA-N
InChI
InChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h11-15,17,20-21H,3-10H2,1-2H3/t11-,12+,13+,14+,15+,17+,18+,19+/m1/s1
IUPAC Name
(3aS,3bR,4S,5aR,7S,9aS,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-one
SMILES

References

General References
Not Available
ChemSpider
8011902
ZINC
ZINC000006067655

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentAlzheimer's Disease (AD)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.102 mg/mLALOGPS
logP2.3ALOGPS
logP2.46ChemAxon
logS-3.5ALOGPS
pKa (Strongest Acidic)18.3ChemAxon
pKa (Strongest Basic)-0.51ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area57.53 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity85.4 m3·mol-1ChemAxon
Polarizability35.56 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on March 19, 2008 10:41 / Updated on June 12, 2020 10:52

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