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Amolimogene bepiplasmid
go.drugbank.com/drugs/DB04904InvestigationalAmolimogene is an investigational therapeutic designed to specifically augment the body's defensive response to human papillomavirus (HPV).
Sapacitabine
go.drugbank.com/drugs/DB06365InvestigationalSynonyms: 1-(2-C-cyano-2-deoxy- ß-D-arabino-pentafuranosyl)-N4-palmitoylcytosineAnti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356Investigational[L27381] To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune response mounted by the chickens towards … These antibodies are currently being investigated against COVID-19 in the trial NCT04567810 (Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV
Reposal
go.drugbank.com/drugs/DB13805ExperimentalReposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.
Human interleukin-6
go.drugbank.com/drugs/DB15060InvestigationalHuman interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).
AP5346
go.drugbank.com/drugs/DB04992InvestigationalAP5346 is designed to target a diaminocyclohexane platinum (Pt) moiety to tumors through pH-sensitive linkage to a 25 kDa hydroxypropylmethacrylamide polymer. It is being pursued by Access Pharmaceuticals, Inc.
AICA ribonucleotide
go.drugbank.com/drugs/DB01700Investigational5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent … The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and is currently of interest as a potential treatment for diabetes by increasing the metabolic activity
Synonyms: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamideZaltoprofen
go.drugbank.com/drugs/DB06737InvestigationalA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
Avotaciclib
go.drugbank.com/drugs/DB16652InvestigationalAvotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).
Briakinumab
go.drugbank.com/drugs/DB05459InvestigationalAs of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe.