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Ivonescimab
go.drugbank.com/drugs/DB18931InvestigationalIvonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Aminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
Lactide, L-
go.drugbank.com/drugs/DB19115InvestigationalLactide, L- is under investigation in clinical trial NCT05450471 (Effectiveness of Endonasal Polymeric Implant for Chronic Rhinosinusitis).
NSI-189
go.drugbank.com/drugs/DB16230InvestigationalNSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder).
CIGB-258 peptide
go.drugbank.com/drugs/DB15809ExperimentalAs of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Idetrexed
go.drugbank.com/drugs/DB21469InvestigationalThe usage of the INN stem '-trexed' in the name indicates that Idetrexed is a antineoplastic; thymidilate synthetase inhibitor. … Idetrexed is under investigation in clinical trial NCT02360345 (Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly). Idetrexed has a monoisotopic molecular weight of 647.22 Da.
Eritoran
go.drugbank.com/drugs/DB04933InvestigationalEritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Bectumomab
go.drugbank.com/drugs/DB04962ExperimentalBectumomab (marketed under the trade name LymphoScan®) is a mouse monoclonal antibody and which it's used to treat non-Hodgkin's lymphoma. It has a radioisotope, technetium (99m TC) which it's added.