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Displaying results 9081 - 9090 of 10000 in total
  1. Drug

    Annamycin

    go.drugbank.com/drugs/DB06420
    Investigational

    Synonyms: 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicinCategories: P-glycoprotein inhibitors
  2. Drug

    TAK-751S

    go.drugbank.com/drugs/DB06432
    Investigational

    TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic _Escherichia coli_.[A260296]

  3. Drug

    Lonafarnib

    go.drugbank.com/drugs/DB06448
    ApprovedInvestigational

    [A224379, A224384, A224389, A224394, A224399] Mechanistically, HGPS is underpinned by a single heterozygous C-to-T mutation at position 1824 of the _LMNA_ gene, which results in the accumulation of an … aberrant farnesylated form of lamin A called progerin in the inner nuclear membrane.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    Aprinocarsen

    go.drugbank.com/drugs/DB06451
    Investigational

    Aprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha.

    Categories: Protein Kinase C, antagonists & inhibitors
  5. Drug

    Meclinertant

    go.drugbank.com/drugs/DB06455
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    IR501

    go.drugbank.com/drugs/DB06464
    Experimental

    IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity.

  7. Drug

    Clomethiazole

    go.drugbank.com/drugs/DB06470
    Investigational

    Clomethiazole is a well-established γ-aminobutyric acid (GABAA)-mimetic drug. It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  8. Drug

    Naxifylline

    go.drugbank.com/drugs/DB06471
    Experimental

    Synonyms: 8-((2S,5,6-exo)-5,6-epoxy-2-norbonyl)-1,3-dipropylxanthineCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Fradafiban

    go.drugbank.com/drugs/DB06472
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Platelet Glycoprotein GPIIb-IIIa Complex, antagonists & inhibitors
  10. Drug

    Ruplizumab

    go.drugbank.com/drugs/DB06475
    Investigational

    Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.