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Displaying results 901 - 910 of 10000 in total
  1. Target

    Serine/threonine-protein kinase Nek11

    go.drugbank.com/bio_entities/BE0004758
    TargetHumans

    Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage.

    Synonyms: Never in mitosis A-related kinase 11
  2. Drug

    Camizestrant

    go.drugbank.com/drugs/DB19218
    ApprovedInvestigational

    [L64117,L64107,L64116] It is the first next-generation oral SERD and complete ER antagonist approved in the first-line setting, and the only one approved for use with all three widely approved CDK4/6 inhibitors … [L64094,L64107] Patients are selected for treatment on the basis of an *ESR1* mutation detected by circulating tumor DNA testing during first-line endocrine therapy, before radiographic disease progression

    Synonyms: 3-pyridinamine, n-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-6,7,8,9-tetrahydro-8-methyl-7-(2,2,2-trifluoroethyl)-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-, N-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamine
  3. Target

    Serine/threonine-protein kinase Nek5

    go.drugbank.com/bio_entities/BE0009499
    TargetHumans

    Synonyms: Never in mitosis A-related kinase 5
  4. Target

    Chloride anion exchanger

    go.drugbank.com/bio_entities/BE0010211
    TransporterHumans

    Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity) … Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094).

    Synonyms: Down-regulated in adenoma
  5. Target

    Serine/threonine-protein kinase Nek7

    go.drugbank.com/bio_entities/BE0017593
    TargetHumans

    Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:19941817, PubMed:31409757).

    Synonyms: Never in mitosis A-related kinase 7
  6. Drug

    Afatinib

    go.drugbank.com/drugs/DB08916
    ApprovedInvestigational

    Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected

  7. Drug

    Deferiprone

    go.drugbank.com/drugs/DB08826
    ApprovedInvestigational

    Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. … Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Hydroxide ion

    go.drugbank.com/drugs/DB14522
    Investigational

    Mixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ion
  9. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. … It functions by preventing resorption of bone[FDA Label][A959].

    Mixtures: BONYL 70 MG/2800 IU TABLET, 12 ADET, BONEX-D 70 MG / 2800 IU TABLET, 4 ADETProducts: FOSAVANCE 70MG/5600 IE TAB
  10. Indication

    Juvenile Cataracts

    go.drugbank.com/conditions/DBCOND0135843
    Drugs: Bendazac
    Synonyms: Cataract in Child