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Finerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigationalFinerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and can also have effects at the androgen, progesterone, and glucocorticoid receptors.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADETDoravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigational[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.
Categories: Antivirals used in combination for the treatment of HIV infections, Cytochrome P-450 SubstratesProducts: PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADETFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, 2022.
Products: ZARZIO® 30 MU/0.5 ML SOLUCION INYECTABLE O PARA PERFUSION EN JERINGA PRECARGADA, NIVESTIM 30 MIO E/0.5 MLBacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnIt is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. … It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis etc.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingSynonyms: 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylateLisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigational[A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first approved by the FDA in April 2008.[A2230] It was also approved by Health Canada in February 2009. … [L48285] Lisdexamfetamine works to treat attention deficit hyperactivity disorder and binge eating disorder [A2230] by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal
Products: VYVANSE CAPSULES 20 mg, VYVANSE® 20 MG CAPSULASNabumetone
go.drugbank.com/drugs/DB00461Approved[A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in the GI tract. … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action.
Mixtures: NuDroxiPAK N-500Categories: COX-2 Inhibitors, Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Clotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedIt is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). … Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].
Synonyms: 1-(α-(2-Chlorophenyl)benzhydryl)imidazole, 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazoleMixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, LINDAZOL-2 ®Terbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088] … Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s and early 1970s.
Mixtures: BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 ML, BRELAX 1,5 MG+66,5 MG/5 ML ŞURUP, 100 MLCategories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsVespula vulgaris venom protein
go.drugbank.com/drugs/DB11033ApprovedVespula vulgaris venom protein is an extract of Vespula vulgaris venom. Vespula vulgaris venom protein is used in allergenic testing.
Mixtures: Mixed Vespid Venom Protein Multidose 13.0 Ml (3900 Mcg), Hymenoptera Venom Product-mixed Vespid Venom Protein (1650 Mcg)Products: ALUTARD SQ Wespengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml), ALUTARD SQ Wespengift 100.000 SQ-E/ml Injektionssuspension (Fortsetzungsbehandlung)Methylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: SOLU - MEDROL 1000 MG.), METHPRED 500 MG