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IK-930
go.drugbank.com/drugs/DB18149InvestigationalIK-930 is an oral, paralog-selective TEAD inhibitor.
RO-5028442
go.drugbank.com/drugs/DB12721InvestigationalRO5028442 has been used in trials studying Autistic Disorder.
ACT-451840
go.drugbank.com/drugs/DB13054InvestigationalACT-451840 has been used in trials studying Malaria.
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineQRX-411
go.drugbank.com/drugs/DB17868ExperimentalQRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein. … It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777]
Galicaftor
go.drugbank.com/drugs/DB14894InvestigationalGalicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 … in Patients With Cystic Fibrosis.).
Nanoparticle Epirubicin
go.drugbank.com/drugs/DB16248InvestigationalIt is a novel [epirubicin] drug-conjugated polymeric micelle. … Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Synonyms: QUINOLINE, 7-FLUORO-6-METHOXY-4-(6-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-Edodekin alfa
go.drugbank.com/drugs/DB15631InvestigationalEdodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic
Zilovertamab vedotin
go.drugbank.com/drugs/DB18457Investigationalmc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin. … Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (