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Claseprubart
go.drugbank.com/drugs/DB22867InvestigationalClaseprubart is under investigation in clinical trial NCT06858579 (A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)).
PLX51107
go.drugbank.com/drugs/DB17543InvestigationalPLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family. … [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin-3-yl)-Zosurabalpin
go.drugbank.com/drugs/DB21539InvestigationalZosurabalpin is under investigation in clinical trial NCT05614895 (A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections). … Zosurabalpin is a small molecule drug.
Gamgertamig
go.drugbank.com/drugs/DB22765InvestigationalOM336 is under investigation in clinical trial NCT07083960 (OM336 in Autoimmune Cytopenias).
Asapiprant
go.drugbank.com/drugs/DB20492InvestigationalAsapiprant is a small molecule drug. … Are Not in Respiratory Failure).
Categories: Heterocyclic Compounds, 1-RingSynonyms: S-555739Tyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalThere have been reports of hypertensive crisis in patients ingesting tyramine-rich diet in conjunction with monoamine oxidase inhibitors (MAOIs). … Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine.
Paquinimod
go.drugbank.com/drugs/DB13118InvestigationalThe disease affects mainly women of fertile age and progresses in flares with relatively symptom free periods in between. … Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease.
Categories: Heterocyclic Compounds, 2-RingAbdavomeran
go.drugbank.com/drugs/DB15695Investigational[L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding immunoglobulin levels and 50% serum neutralizing titers higher than those observed in [COVID … [L15012] BNT162b1 is undergoing further evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701).
Synonyms: BNT162b1 SARS-CoV-2 VaccineBacteriochlorophyll A
go.drugbank.com/drugs/DB01853ExperimentalA specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.
Synonyms: Bacterio-chlorophyll A, Bacteriochlorophyll ACavosonstat
go.drugbank.com/drugs/DB14775InvestigationalCavosonstat is under investigation in clinical trial NCT02589236 (Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation).