Cavosonstat

DB14775InvestigationalSmall molecule

Cavosonstat is under investigation in clinical trial NCT02589236 (Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation).

Mechanism: Pharmacologically active on Alcohol dehydrogenase class-3
Curator reviewed
Formula / weight: C₁₆H₁₀ClNO₃ · 299.71 g/mol (avg)
Code names: N91115

Resolves to

Compound

UNIIO2Z8Q22ZE4CAS1371587-51-7ChEMBLCHEMBL3989910

Clinical / RWD

PharmGKBPA166163226

Structure

InChIKeyBXSZILNGNMDGSL-UHFFFAOYSA-NSMILESOC(=O)C1=CC(Cl)=C(C=C1)C1=NC2=CC=C(O)C=C2C=C1

Targets

P11766ADH5

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

8Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Cavosonstat, and which of those have an active Phase 3 trial?

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