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Displaying results 9131 - 9140 of 10000 in total
  1. Drug

    ENTR-601-44

    go.drugbank.com/drugs/DB17836
    Investigational

    ENTR-601-44 is an exon 44 skipping phosphorodiamidate morpholino oligonucleotide (PMO). Developed by Entrada Therapeutics, it was investigated for the treatment of Duchenne muscular dystrophy.[L46641]

  2. Drug

    PAS-004

    go.drugbank.com/drugs/DB18611
    Investigational

    PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.

  3. Drug

    Human interleukin-6

    go.drugbank.com/drugs/DB15060
    Investigational

    Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

    Synonyms: HUMAN B-CELL STIMULATORY FACTOR 2, IL-6
  4. Drug

    Brivoligide

    go.drugbank.com/drugs/DB16116
    Investigational

    Brivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).

    Synonyms: D(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1), Dna, d(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1)
  5. Drug

    Cardiopet

    go.drugbank.com/drugs/DB18913
    Investigational

    Cardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).

    Synonyms: 2-((1s,2r)-2-(5-(fluoro-18f)tridecyl)cyclopropyl)acetic acid, Trans-9(rs)-18f-fluoro-3,4(rs,rs)-methyleneheptadecanoic acid
  6. Drug

    Dovitinib

    go.drugbank.com/drugs/DB05928
    Investigational

    Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. … Chiron currently has three ongoing Phase I clinical trials for dovitinib.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 Inducers
  7. Drug

    Guanabenz

    go.drugbank.com/drugs/DB00629
    ApprovedWithdrawn

    Guanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

    Categories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AgonistsSynonyms: N-(2,6-DICHLOROBENZYLIDENE)-N'-AMIDINOHYDRAZINE, 2-((2,6-DICHLOROPHENYL)METHYLENE)HYDRAZINECARBOXIMIDAMIDE
  8. Drug

    Povidone K30

    go.drugbank.com/drugs/DB14478
    Approved

    A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See [povidone] for full details.

    Synonyms: 1-vinylpyrrolidin-2-one homopolymer, PVP K-30Products: Povidone K-30
  9. Drug

    Pardoprunox

    go.drugbank.com/drugs/DB12061
    Investigational

    Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. … Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    Gaboxadol

    go.drugbank.com/drugs/DB06554
    Investigational

    Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing … It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol