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Nanoparticle Epirubicin
go.drugbank.com/drugs/DB16248InvestigationalIt is a novel [epirubicin] drug-conjugated polymeric micelle. … Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Synonyms: QUINOLINE, 7-FLUORO-6-METHOXY-4-(6-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-Antipain
go.drugbank.com/drugs/DB15251Experimental[A214484, A214487] Antipain was used in 2010 to obtain a crystal structure of the _Leishmania major_ oligopeptidase B (OPB), a serine protease that serves as a virulence factor in trypanosomatids. … [A214481] Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as _N_-methyl-_N_'-nitro
Perfluorodecalin
go.drugbank.com/drugs/DB16292InvestigationalSkin Removal From the Thigh - a Study in "Split Wound Design"). … Perfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split
Synonyms: Fluosol da perfluorodecalinGatralimab
go.drugbank.com/drugs/DB16528InvestigationalGatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial
Tarcocimab tedromer
go.drugbank.com/drugs/DB18937InvestigationalTarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately
Synonyms: Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal OG1950 g1-chain), disulfide with human-Mus musculusNBF-006
go.drugbank.com/drugs/DB21770InvestigationalNBF-006 is under investigation in clinical trial NCT03819387 (A Study of NBF-006 in Non-small Cell Lung, Pancreatic, or Colorectal Cancer). … This drug is a proprietary siRNA-based lyophilized lipid nanoparticle (LNP).[A273775, L52905]
Ginsenoside Rg1
go.drugbank.com/drugs/DB06750ExperimentalNutraceuticalGinsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). … Rg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng). It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates estrogen-like activity.
Synonyms: Panaxoside ALicofelone
go.drugbank.com/drugs/DB04725ExperimentalAlthough phase III trials have been successfully completed in OA patients no dates for regulatory submission have yet been given. … It is currently under evaluation as a treatment for osteoarthritis (OA), the most common form of arthritis.
Acetic acid C-11
go.drugbank.com/drugs/DB15111InvestigationalAcetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and