Antipain

DB15251ExperimentalSmall molecule

Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells... Antipain was used in 2010 to obtain a crystal structure of the Leishmania major oligopeptidase B (OPB), a serine protease that serves as a virulence factor in trypanosomatids.

Chemical structure of Antipain
Formula / weight
C27H44N10O6 · 604.713 g/mol (avg)

Resolves to

Compound
UNII47V479BE6LCAS37691-11-5ChEMBLCHEMBL1230912
Structure
InChIKeySDNYTAYICBFYFH-TUFLPTIASA-NSMILESCC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C=O
Targets
P07858CTSBP07477PRSS1Q15661TPSAB1

What you can answer from here — as of July 08, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
10+ReferencesStructured and connected to the statements they support
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